Lupeol is a natural triterpenoid that widely exists in edible fruits and vegetables, and
medicinal plants. In the last decade, a plethora of studies on the pharmacological activities …

The saponins are a diverse class of natural products, with a broad scale distribution across
different plant species. Chemically characterized as triterpenoid glycosides, they posses a …

Vegetal origin agro-industrial wastes are seen as a problem since the beginning of the
industrial processes; however, they are becoming attractive as raw material for numerous …

Hypoxia is a feature of all solid tumours, contributing to tumour progression. Activation of HIF-
1α plays a critical role in promoting tumour angiogenesis and metastasis. Since its …

Background Hypoxic microenvironment is a common feature of solid tumors, which leads to
the promotion of cancer. The transcription factor, HIF-1α, expressed under hypoxic …

Hypoxia is an important module in all solid tumours to promote angiogenesis, invasion and
metastasis. Stabilization and subsequent nuclear localization of HIF-1α subunits result in the …

In this study, the bioactivity‐guided fractionation was conducted on the aerial parts of
Arctium lappa L. and then the extracts were tested in vitro on breast cancer (MCF‐7) …

Vasculogenic mimicry, an endothelia-independent tumor microcirculation has been found in
various cancers and is thought to be achieved by cancer stem like cells. Dacarbazine …

A series of oxadiazole derivatives possessing morpholine 6a–l were synthesized by
nucleophilic substitution reaction of key intermediates [1, 3, 4]-oxadiazole-2-thiol derivatives …

Background Angiogenesis is a hallmark feature in the initiation, progression and growth of
tumour. There are various factors for promotion of angiogenesis on one hand and on the …