Self-nano-emulsifying drug-delivery systems: From the development to the current applications and challenges in oral drug delivery
Approximately one third of newly discovered drug molecules show insufficient water
solubility and therefore low oral bio-availability. Self-nano-emulsifying drug-delivery systems …
solubility and therefore low oral bio-availability. Self-nano-emulsifying drug-delivery systems …
Treatment strategies against diabetes: Success so far and challenges ahead
R Khursheed, SK Singh, S Wadhwa, B Kapoor… - European journal of …, 2019 - Elsevier
The growing disease burden of diabetes mellitus is an important public health concern,
affecting over 400 million people globally. This epidemic, if not controlled in time, leads to …
affecting over 400 million people globally. This epidemic, if not controlled in time, leads to …
[HTML][HTML] Multifunctional oral delivery systems for enhanced bioavailability of therapeutic peptides/proteins
Y Han, Z Gao, L Chen, L Kang, W Huang, M Jin… - … Pharmaceutica Sinica B, 2019 - Elsevier
In last few years, therapeutic peptides/proteins are rapidly growing in drug market
considering their higher efficiency and lower toxicity than chemical drugs. However, the …
considering their higher efficiency and lower toxicity than chemical drugs. However, the …
Oral nano drug delivery systems for the treatment of type 2 diabetes mellitus: an available administration strategy for antidiabetic phytocompounds
X Nie, Z Chen, L Pang, L Wang, H Jiang… - International journal …, 2020 - Taylor & Francis
In view of the worldwide serious health threat of type 2 diabetes mellitus (T2DM), natural
sources of chemotherapies have been corroborated as the promising alternatives, with the …
sources of chemotherapies have been corroborated as the promising alternatives, with the …
Recent trends of self-emulsifying drug delivery system for enhancing the oral bioavailability of poorly water-soluble drugs
P Tran, JS Park - Journal of Pharmaceutical Investigation, 2021 - Springer
Background The oral route is the most popular route for the clinical administration of drugs to
treat various diseases. Before a drug is absorbed into the blood circulation, it must undergo …
treat various diseases. Before a drug is absorbed into the blood circulation, it must undergo …
Enhanced oral bioavailability and neuroprotective effect of fisetin through its SNEDDS against rotenone-induced Parkinson's disease rat model
Fisetin (FS) was reported to have various pharmacological activities. But due to its lower
aqueous solubility and oral bioavailability, it is not in much use. As solubility and …
aqueous solubility and oral bioavailability, it is not in much use. As solubility and …
Polysaccharide, fecal microbiota, and curcumin-based novel oral colon-targeted solid self-nanoemulsifying delivery system: Formulation, characterization, and in-vitro …
The use of polysaccharides in preparation of microbially triggered colon-targeted delivery
system has been explored extensively to deliver drugs at the colonic site. This type of …
system has been explored extensively to deliver drugs at the colonic site. This type of …
Inhalation drug delivery in combating pulmonary infections: Advances and challenges
Pulmonary infections (PIs) are contributing as a significant cause of mortality across the
world. The clinical applications of a variety of therapeutics approved for PIs have been …
world. The clinical applications of a variety of therapeutics approved for PIs have been …
Exploring role of probiotics and Ganoderma lucidum extract powder as solid carriers to solidify liquid self-nanoemulsifying delivery systems loaded with curcumin
Solid self-nanoemulsifying drug delivery system (S-SENDDS) containing Curcumin (CRM)
were prepared using combination of Ganoderma lucidum extract powder (GLEP) and …
were prepared using combination of Ganoderma lucidum extract powder (GLEP) and …
Development of guar gum-pectin-based colon targeted solid self-nanoemulsifying drug delivery system of xanthohumol
Present study deciphers development of oral polysaccharide-based colon targeted solid self-
nanoemulsifying drug delivery system (S-SNEDDS) of xanthohumol (XH). Several studies …
nanoemulsifying drug delivery system (S-SNEDDS) of xanthohumol (XH). Several studies …