Nitric oxide (NO) is an important signaling molecule that is involved in a wide range of
physiological and pathological events in biology. Metal coordination chemistry, especially …

A growing subset of metalloenzymes activates dioxygen with nonheme diiron active sites to
effect substrate oxidations that range from the hydroxylation of methane and the …

Activation of dinitrogen plays an important role in daily anthropogenic life, and the processes
by which this fixation occurs have been a longstanding and significant research focus within …

In recent years, significant progress has been made in understanding the geometric and
electronic structures of the active sites of non-heme iron enzymes and the contributions of …

A molecular description of oxygen and peroxide activation in biological systems is difficult,
because electrons liberated during X-ray data collection reduce the active centres of redox …

Protein Radicals in Enzyme Catalysis. [Chem. Rev. 1998, 98, 705−762 | Chemical Reviews ACS
ACS Publications C&EN CAS Find my institution Log In Chemical Reviews ACS Publications …

Ribonucleotide reductases (RNRs) catalyze the conversion of nucleotides to
deoxynucleotides in all organisms (eq 1). 1-3 These enzymes play an essential role in DNA …

Ribonucleotide reductases provide the building blocks for DNA replication in all living cells.
Three different classes of enzymes use protein free radicals to activate the substrate …

Metalloproteins perform a variety of functions in biological systems. The catalysis of several
remarkable chemical transformations occurs at metal centers embedded in the active sites of …

Ribonucleotide reductase (RNR) is the enzyme responsible for the conversion of
ribonucleotides to 2′-deoxyribonucleotides and thereby provides the precursors needed …