Splitsville: structural and functional insights into the dynamic bacterial Z ring
DP Haeusser, W Margolin - Nature Reviews Microbiology, 2016 - nature.com
Bacteria must divide to increase in number and colonize their niche. Binary fission is the
most widespread means of bacterial cell division, but even this relatively simple mechanism …
most widespread means of bacterial cell division, but even this relatively simple mechanism …
Targeting the achilles heel of FtsZ: The interdomain cleft
Widespread antimicrobial resistance among bacterial pathogens is a serious threat to public
health. Thus, identification of new targets and development of new antibacterial agents are …
health. Thus, identification of new targets and development of new antibacterial agents are …
Bacterial FtsZ protein forms phase‐separated condensates with its nucleoid‐associated inhibitor SlmA
B Monterroso, S Zorrilla, M Sobrinos‐Sanguino… - EMBO …, 2019 - embopress.org
Macromolecular condensation resulting from biologically regulated liquid–liquid phase
separation is emerging as a mechanism to organize intracellular space in eukaryotes, with …
separation is emerging as a mechanism to organize intracellular space in eukaryotes, with …
Host defense (antimicrobial) peptides
E Sun, CR Belanger, EF Haney… - Peptide applications in …, 2018 - Elsevier
Small cationic, amphipathic peptides with critical roles in host defenses often exhibit
overlapping but distinct immunomodulatory activity, direct antimicrobial activity towards …
overlapping but distinct immunomodulatory activity, direct antimicrobial activity towards …
OxyS small RNA induces cell cycle arrest to allow DNA damage repair
S Barshishat, M Elgrably‐Weiss, J Edelstein… - The EMBO …, 2018 - embopress.org
To maintain genome integrity, organisms employ DNA damage response, the underlying
principles of which are conserved from bacteria to humans. The bacterial small RNA OxyS of …
principles of which are conserved from bacteria to humans. The bacterial small RNA OxyS of …
Bacterial division ring stabilizing ZapA versus destabilizing SlmA modulate FtsZ switching between biomolecular condensates and polymers
B Monterroso, MÁ Robles-Ramos… - Open …, 2023 - royalsocietypublishing.org
Cytokinesis is a fundamental process for bacterial survival and proliferation, involving the
formation of a ring by filaments of the GTPase FtsZ, spatio-temporally regulated through the …
formation of a ring by filaments of the GTPase FtsZ, spatio-temporally regulated through the …
[HTML][HTML] Benzodioxane-benzamides as promising inhibitors of Escherichia coli FtsZ
L Suigo, B Monterroso, M Sobrinos-Sanguino… - International Journal of …, 2023 - Elsevier
The conserved process of cell division in bacteria has been a long-standing target for
antimicrobials, although there are few examples of potent broad-spectrum compounds that …
antimicrobials, although there are few examples of potent broad-spectrum compounds that …
Bacteriophage encapsulation–Trends and potential applications in aquaculture
Bacterial infections pose significant threats to farmed aquatic animals, with diseases such as
Motile Aeromonas Septicaemia (MAS), Streptococcosis, Edwardsiellosis, and Vibriosis …
Motile Aeromonas Septicaemia (MAS), Streptococcosis, Edwardsiellosis, and Vibriosis …
[HTML][HTML] Unite to divide: Oligomerization of tubulin and actin homologs regulates initiation of bacterial cell division
M Krupka, W Margolin - F1000Research, 2018 - ncbi.nlm.nih.gov
To generate two cells from one, bacteria such as Escherichia coli use a complex of
membrane-embedded proteins called the divisome that synthesize the division septum. The …
membrane-embedded proteins called the divisome that synthesize the division septum. The …
A clade of RHH proteins ubiquitous in Sulfolobales and their viruses regulates cell cycle progression
X Li, C Lozano-Madueño… - Nucleic Acids …, 2023 - academic.oup.com
Cell cycle regulation is crucial for all living organisms and is often targeted by viruses to
facilitate their own propagation, yet cell cycle progression control is largely underexplored in …
facilitate their own propagation, yet cell cycle progression control is largely underexplored in …