Pathogenesis and virulence of Candida albicans

JP Lopes, MS Lionakis - Virulence, 2022 - Taylor & Francis
Candida albicans is a commensal yeast fungus of the human oral, gastrointestinal, and
genital mucosal surfaces, and skin. Antibiotic-induced dysbiosis, iatrogenic …

The impact of the Fungus-Host-Microbiota interplay upon Candida albicans infections: current knowledge and new perspectives

C d'Enfert, AK Kaune, LR Alaban… - FEMS microbiology …, 2021 - academic.oup.com
Candida albicans is a major fungal pathogen of humans. It exists as a commensal in the oral
cavity, gut or genital tract of most individuals, constrained by the local microbiota, epithelial …

Immune regulation by fungal strain diversity in inflammatory bowel disease

XV Li, I Leonardi, GG Putzel, A Semon, WD Fiers… - Nature, 2022 - nature.com
The fungal microbiota (mycobiota) is an integral part of the complex multikingdom microbial
community colonizing the mammalian gastrointestinal tract and has an important role in …

[HTML][HTML] Invasive candidiasis

PG Pappas, MS Lionakis, MC Arendrup… - Nature Reviews …, 2018 - nature.com
Invasive candidiasis is an important health-care-associated fungal infection that can be
caused by several Candida spp.; the most common species is Candida albicans, but the …

Immune defence against Candida fungal infections

MG Netea, LAB Joosten, JWM Van Der Meer… - Nature Reviews …, 2015 - nature.com
The immune response to Candida species is shaped by the commensal character of the
fungus. There is a crucial role for discerning between colonization and invasion at mucosal …

Fungal dysbiosis: immunity and interactions at mucosal barriers

ID Iliev, I Leonardi - Nature Reviews Immunology, 2017 - nature.com
Fungi and mammals share a co-evolutionary history and are involved in a complex web of
interactions. Studies focused on commensal bacteria suggest that pathological changes in …

Candida albicans Antifungal Resistance and Tolerance in Bloodstream Infections: The Triad Yeast-Host-Antifungal

S Costa-de-Oliveira, AG Rodrigues - Microorganisms, 2020 - mdpi.com
Candida albicans represents the most frequent isolated yeast from bloodstream infections.
Despite the remarkable progress in diagnostic and therapeutic approaches, these infections …

Microbiota sensing by Mincle-Syk axis in dendritic cells regulates interleukin-17 and-22 production and promotes intestinal barrier integrity

M Martinez-Lopez, S Iborra, R Conde-Garrosa… - Immunity, 2019 - cell.com
Summary Production of interleukin-17 (IL-17) and IL-22 by T helper 17 (Th17) cells and
group 3 innate lymphoid cells (ILC3s) in response to the gut microbiota ensures …

IL-17–Mediated immunity to the opportunistic fungal pathogen Candida albicans

HR Conti, SL Gaffen - The Journal of Immunology, 2015 - journals.aai.org
Abstract IL-17 (IL-17A) has emerged as a key mediator of protection against extracellular
microbes, but this cytokine also drives pathology in various autoimmune diseases …

Gut mycobiota in immunity and inflammatory disease

XV Li, I Leonardi, ID Iliev - Immunity, 2019 - cell.com
The mammalian intestine is colonized by a wealth of microorganisms—including bacteria,
viruses, protozoa, and fungi—that are all integrated into a functional trans-kingdom …