Frontotemporal lobar degeneration causes a spectrum of complex degenerative disorders
including frontotemporal dementia, progressive supranuclear palsy and corticobasal …

Recent years have seen a rapid increase in the number of studies using evidence-
accumulation models (such as the drift diffusion model, DDM) in the fields of psychology and …

Neuroimaging increasingly exploits machine learning techniques in an attempt to achieve
clinically relevant single-subject predictions. An alternative to machine learning, which tries …

Apathy and impulsivity are common and disabling consequences of frontotemporal lobar
degeneration. They cause substantial carer distress, but their aetiology remains elusive …

Behavioural disinhibition is a common feature of the syndromes associated with
frontotemporal lobar degeneration (FTLD). It is associated with high morbidity and lacks …

Progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS; the most common
phenotype of corticobasal degeneration) are tauopathies with a relentless course, usually …

Combining walking with a demanding cognitive task is traditionally expected to elicit
decrements in gait and/or cognitive task performance. However, it was recently shown that …

Parkinson's disease (PD) and progressive supranuclear palsy (PSP) both impair response
inhibition, exacerbating impulsivity. Inhibitory control deficits vary across individuals and are …

Disinhibition, mainly caused by damage in frontotemporal brain regions, is one of the major
causes of caregiver distress in neurodegenerative dementias. Behavioural inhibition deficits …

The distribution of pathology in frontotemporal dementia is anatomically selective, to distinct
cortical regions and with differential neurodegeneration across the cortical layers. The …