The demand for portable and wearable chemical or biosensors and their expeditious
development in recent years has created a scientific challenge in terms of their continuous …

Rho kinase (ROCK) is a major downstream effector of the small GTPase RhoA. ROCK
family, consisting of ROCK1 and ROCK2, plays central roles in the organization of actin …

Rho kinase (ROCK) belongs to the AGC (PKA/PKG/PKC) family of serine/threonine kinases
and is a major downstream effector of the small GTPase RhoA. ROCK plays central roles in …

As a major ingredient of Radix ginseng, ginsenoside Rg1 (Rg1) has been increasingly
recognized to benefit the heart condition, however, the rationale behind the role is not fully …

Cardiac ischemia and reperfusion (I/R) injury remains a challenge for clinicians.
Ginsenoside Rb1 (Rb1) has been reported to have the ability to attenuate I/R injury, but its …

Cardiac ischemia-reperfusion (I/R) injury remains a challenge for clinicians, which initiates
with energy metabolism disorder. The present study was designed to investigate the …

Large‐scale screening of molecules heavily relies on phenotyping of small living organisms
during preclinical development. However, deep profiling candidate therapeutics on whole …

Background: Gualou Xiebai Decoction (GLXB) is a classic prescription of Chinese medicine
used for the treatment of cardiac problems. The present study was designed to explore the …

The development of new drugs requires high-throughput and cost-effective pharmacological
assessment in relevant biological models. Here, we introduce a novel pharmacological …

Background: Protein kinases are the enzymes involved in phosphorylation of different
proteins which leads to functional changes in those proteins. They belong to serine …