Membrane rafts are dynamic, small (10–200 nm) domains enriched with cholesterol and
sphingolipids that compartmentalize cellular processes. Rafts participate in roles essential to …

Recent work has identified three distinct classes of viral membrane fusion proteins based on
structural criteria. In addition, there are at least four distinct mechanisms by which viral fusion …

Dengue virus enters a host cell when the viral envelope glycoprotein, E, binds to a receptor
and responds by conformational rearrangement to the reduced pH of an endosome. The …

Alphaviruses are small, spherical, enveloped, positive-sense ssRNA viruses responsible for
a considerable number of human and animal diseases. Alphavirus members include …

▪ Abstract Disparate biological processes involve fusion of two membranes into one and
fission of one membrane into two. To formulate the possible job description for the proteins …

Background A Chikungunya (CHIK) outbreak hit La Réunion Island in 2005–2006. The
implicated vector was Aedes albopictus. Here, we present the first study on the susceptibility …

As intracellular parasites, viruses rely heavily on the use of numerous cellular machineries
for completion of their replication cycle. The recent discovery of the heterogeneous …

Abstract Structure–function studies have defined two classes of viral membrane-fusion
proteins that have radically different architectures but adopt a similar overall'hairpin' …

Throughout evolution, organisms have developed immune-surveillance networks to protect
themselves from potential pathogens. At the cellular level, the signalling events that regulate …

Influenza virus has been described to enter host cells via clathrin-mediated endocytosis.
However, it has also been suggested that other endocytic routes may provide additional …