The cryopreservation of spermatozoa was introduced in the 1960s as a route to fertility
preservation. Despite the extensive progress that has been made in this field, the biological …

Reactive oxygen species (ROS) generated at low levels during mitochondrial respiration
have key roles in several signaling pathways. Oxidative stress (OS) arises when the …

Oocytes and preimplantation embryos require careful regulation of the redox environment
for optimal development both in vivo and in vitro. Reactive oxygen species (ROS) are …

In brief Reactive oxygen species are generated throughout the pre-implantation period and
are necessary for normal embryo formation. However, at pathological levels, they result in …

Reproductive diseases have become a growing worldwide problem and male factor plays
an important role in the reproductive diagnosis, prognosis and design of assisted …

In a society where women often want successful careers and equal opportunities to men, the
early nature of ovarian aging often forces women to make difficult life choices between …

This is a short review of the basic molecular mechanisms of ovarian aging, written with a
particular focus on the use of this data to improve the diagnostic and therapeutic protocols …

Subjects increasing sperm DNA fragmentation (sDF) during Density Gradient Centrifugation
(DGC), a common sperm selection procedure in Assisted Reproduction Techniques (ARTs) …

The fundamental underlying paradigm of sexual reproduction is the production of male and
female gametes of sufficient genetic difference and quality that, following syngamy, they …

Sperm DNA fragmentation (SDF) testing has been emerging as a valuable tool for male
fertility evaluation. While the essential role of sperm DNA integrity in human reproduction …