Background Aedes aegypti is the main vector of the virus causing Dengue fever, a disease
that has increased dramatically in importance in recent decades, affecting many tropical and …

The need for improved dengue vaccines remains since the only licensed vaccine,
Dengvaxia, shows variable efficacy depending on the infecting dengue virus (DENV) type …

This study presents the results obtained in the monitoring of dengue virus (DENV)
transmission in the Greater Metropolitan Region of the State of Rio de Janeiro, in the period …

Espirito Santo virus (ESV) is a newly discovered virus recovered as contamination in a
sample of a virulent strain of dengue-2 virus (strain 44/2), which was recovered from a …

Dengue fever, caused by the dengue virus (DENV‐1,− 2,− 3, and− 4), affects millions of
people in the tropical and subtropical regions worldwide. Severe dengue is correlated with …

Among the flaviviruses, dengue, with its four serotypes, has spread throughout the tropics.
The most advanced vaccines developed so far include live attenuated viruses, which have …

The macaque is widely accepted as a suitable model for preclinical characterization of
dengue vaccine candidates. However, the only vaccine for which both preclinical and …

Dengue is a mosquito-borne viral infection that in recent decades has become a major
international public health concern. Epidemic dengue fever reemerged in Brazil in 1981 …

Molecular Genomic Approaches to Infectious Diseases in Resource-Limited Settings | PLOS
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The genomic sequences of the Envelope-Non-Structural protein 1 junction region (E/NS1) of
84 DEN-1 and 22 DEN-2 isolates from Brazil were determined. Most of these strains were …