Enjoy the trip: calcium in mitochondria back and forth
In the last 5 years, most of the molecules that control mitochondrial Ca2+ homeostasis have
been finally identified. Mitochondrial Ca2+ uptake is mediated by the Mitochondrial Calcium …
been finally identified. Mitochondrial Ca2+ uptake is mediated by the Mitochondrial Calcium …
ATP synthesis and storage
Since 1929, when it was discovered that ATP is a substrate for muscle contraction, the
knowledge about this purine nucleotide has been greatly expanded. Many aspects of cell …
knowledge about this purine nucleotide has been greatly expanded. Many aspects of cell …
Store-operated calcium channels
AB Parekh, JW Putney Jr - Physiological reviews, 2005 - journals.physiology.org
In electrically nonexcitable cells, Ca2+ influx is essential for regulating a host of kinetically
distinct processes involving exocytosis, enzyme control, gene regulation, cell growth and …
distinct processes involving exocytosis, enzyme control, gene regulation, cell growth and …
Inositol Trisphosphate Receptor Ca2+ Release Channels
The inositol 1, 4, 5-trisphosphate (InsP3) receptors (InsP3Rs) are a family of Ca2+ release
channels localized predominately in the endoplasmic reticulum of all cell types. They …
channels localized predominately in the endoplasmic reticulum of all cell types. They …
Microdomains of Intracellular Ca2+: Molecular Determinants and Functional Consequences
Calcium ions are ubiquitous and versatile signaling molecules, capable of decoding a
variety of extracellular stimuli (hormones, neurotransmitters, growth factors, etc.) into …
variety of extracellular stimuli (hormones, neurotransmitters, growth factors, etc.) into …
[HTML][HTML] Ca2+ transfer from the ER to mitochondria: when, how and why
The heterogenous subcellular distribution of a wide array of channels, pumps and
exchangers allows extracellular stimuli to induce increases in cytoplasmic Ca2+ …
exchangers allows extracellular stimuli to induce increases in cytoplasmic Ca2+ …
[HTML][HTML] Recombinant expression of the voltage-dependent anion channel enhances the transfer of Ca2+ microdomains to mitochondria
Although the physiological relevance of mitochondrial Ca 2+ homeostasis is widely
accepted, no information is yet available on the molecular identity of the proteins involved in …
accepted, no information is yet available on the molecular identity of the proteins involved in …
[HTML][HTML] Control of mitochondrial motility and distribution by the calcium signal: a homeostatic circuit
M Yi, D Weaver, G Hajnóczky - The Journal of cell biology, 2004 - ncbi.nlm.nih.gov
Mitochondria are dynamic organelles in cells. The control of mitochondrial motility by
signaling mechanisms and the significance of rapid changes in motility remains elusive. In …
signaling mechanisms and the significance of rapid changes in motility remains elusive. In …
Contributions of mitochondria to animal physiology: from homeostatic sensor to calcium signalling and cell death
MR Duchen - The Journal of physiology, 1999 - Wiley Online Library
Over recent years, it has become clear that mitochondria play a central role in many key
aspects of animal physiology and pathophysiology. Their central and ubiquitous task is …
aspects of animal physiology and pathophysiology. Their central and ubiquitous task is …
Mitochondria as all‐round players of the calcium game
Although it has been known for over three decades that mitochondria are endowed with a
complex array of Ca2+ transporters and that key enzymes of mitochondrial metabolism are …
complex array of Ca2+ transporters and that key enzymes of mitochondrial metabolism are …