The increasingly recognized role of different types of B cells and plasma cells in protective
and pathogenic immune responses combined with technological advances have generated …

The success of vaccines is dependent on the generation and maintenance of immunological
memory. The immune system can remember previously encountered pathogens, and …

These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical …

Tumours often contain B cells and plasma cells but the antigen specificity of these
intratumoral B cells is not well understood,,,,,,–. Here we show that human papillomavirus …

Success with B cell depletion using rituximab has proven the concept that B lineage cells
represent a valid target for the treatment of autoimmune diseases, and has promoted the …

The third edition of Flow Cytometry Guidelines provides the key aspects to consider when
performing flow cytometry experiments and includes comprehensive sections describing …

It is now well accepted that plasma cells can become long-lived (memory) plasma cells and
secrete antibodies for months, years or a lifetime. However, the mechanisms involved in this …

B cells are essential for humoral immunity, but the role that they have in regulating CD4+ T
cell responses remains controversial. However, new data showing that the transient …

To advance our understanding and treatment of disease, research immunologists have
been called-upon to place more centralized emphasis on impactful human studies. Such …

▪ Abstract In vertebrates, serum antibodies are an essential component of innate and
adaptive immunity and immunological memory. They also can contribute significantly to …