Global birth prevalence of spina bifida by folic acid fortification status: a systematic review and meta-analysis

CAM Atta, KM Fiest, AD Frolkis… - … journal of public …, 2016 - ajph.aphapublications.org
Background. Birth defects remain a significant source of worldwide morbidity and mortality.
Strong scientific evidence shows that folic acid fortification of a region's food supply leads to …

Spina bifida

AJ Copp, NS Adzick, LS Chitty, JM Fletcher… - Nature reviews Disease …, 2015 - nature.com
Spina bifida is a birth defect in which the vertebral column is open, often with spinal cord
involvement. The most clinically significant subtype is myelomeningocele (open spina …

Folic acid and primary prevention of neural tube defects: A review

JD van Gool, H Hirche, H Lax… - Reproductive …, 2018 - Elsevier
With 4 mg folic acid daily, it may take 20 weeks to reach red-blood-cell folate levels between
1050 and 1340 nmol/L, optimal for reduction of the neural tube defect risk. Therefore, folic …

Micronutrient fortification of food and its impact on woman and child health: a systematic review

JK Das, RA Salam, R Kumar, ZA Bhutta - Systematic reviews, 2013 - Springer
Background Vitamins and minerals are essential for growth and metabolism. The World
Health Organization estimates that more than 2 billion people are deficient in key vitamins …

Impact of folic acid fortification of flour on neural tube defects: a systematic review

C Castillo-Lancellotti, JA Tur, R Uauy - Public health nutrition, 2013 - cambridge.org
ObjectiveTo review the impact of folic acid fortification of flour on the prevalence of neural
tube defects (NTD). DesignSystematic review of the literature on MEDLINE via PubMed …

Global prevalence of congenital anencephaly: a comprehensive systematic review and meta-analysis

N Salari, B Fatahi, R Fatahian, P Mohammadi… - Reproductive health, 2022 - Springer
Background Anencephaly is a fatal congenital anomaly characterized by the absence of
brain hemispheres and cranial arch. Timely preventive measures can be taken by knowing …

Folic acid flour fortification: impact on the frequencies of 52 congenital anomaly types in three South American countries

JS López‐Camelo, EE Castilla… - American Journal of …, 2010 - Wiley Online Library
The aim of the present investigation was to search for a reduction in birth prevalence
estimates of 52 selected types of congenital anomalies, associated with folic acid fortification …

Neural tube defects in Latin America and the impact of fortification: a literature review

J Rosenthal, J Casas, D Taren, CJ Alverson… - Public health …, 2014 - cambridge.org
ObjectiveData on the prevalence of birth defects and neural tube defects (NTD) in Latin
America are limited. The present review summarizes NTD prevalence and time trends in …

[HTML][HTML] Folate fortification and supplementation in prevention of folate-sensitive neural tube defects: a systematic review of policy

NA Shlobin, MA LoPresti, RY Du, S Lam - Journal of Neurosurgery …, 2020 - thejns.org
OBJECTIVE Neural tube defects (NTDs) are common congenital neurological defects,
resulting in mortality, morbidity, and impaired quality of life for patients and caregivers. While …

[HTML][HTML] Epidemiology, prenatal management, and prevention of neural tube defects

MA Salih, WR Murshid, MZ Seidahmed - Saudi medical journal, 2014 - ncbi.nlm.nih.gov
This review article discusses the epidemiology, risk factors, prenatal screening, diagnosis,
prevention potentials, and epidemiologic impact of neural tube defects (NTDs). The average …