Approximately 50% of patients with cancer will develop skeletal metastases, which often
lead to significant pain. When a patient complains of pain, a bone scan and/or plain x-rays …

Abstract Purpose of Review Skeletal metastasis involves the uncoupling of physiologic bone
remodeling resulting in abnormal bone turnover and radical changes in bony architecture …

Objective To describe the quantitative image quality and histogram-based evaluation of an
iterative reconstruction (IR) algorithm in chest computed tomography (CT) scans at low-to …

Purpose To determine a threshold of vertebral body (VB) osteolytic or osteoblastic tumor
involvement that would predict vertebral compression fracture (VCF) risk after stereotactic …

Quantitative assessment of metastatic disease in bone is often considered immeasurable
and, as such, patients with skeletal metastases are often excluded from clinical trials. In …

Study Design. A comparative analysis of parametric and patient-specific finite element (FE)
modeling of spinal motion segments. Objectives. To develop patient-specific FE models of …

Objective To describe the quantitative image quality and histogram-based evaluation of an
iterative reconstruction (IR) algorithm in chest computed tomography (CT) scans at low-to …

The vertebral column is the most frequent site of metastatic involvement of the skeleton with
up to 1/3 of all cancer patients developing spinal metastases. Longer survival times for …

The early detection of bone metastases is important for determining the prognosis and
treatment of a patient. We developed a CAD system which detects sclerotic bone metastases …

Metastatic disease in the vertebral column compromises the structural stability of the spine
leading to increased risk of fracture. The complex patterns of osteolytic and osteoblastic …