COVID-19 annual update: a narrative review

M Biancolella, VL Colona, L Luzzatto, JL Watt… - Human genomics, 2023 - Springer
Three and a half years after the pandemic outbreak, now that WHO has formally declared
that the emergency is over, COVID-19 is still a significant global issue. Here, we focus on …

Host range, transmissibility and antigenicity of a pangolin coronavirus

YJ Hou, S Chiba, SR Leist, RM Meganck… - Nature …, 2023 - nature.com
The pathogenic and cross-species transmission potential of SARS-CoV-2-related
coronaviruses (CoVs) remain poorly characterized. Here we recovered a wild-type pangolin …

[HTML][HTML] The natural virome and pandemic potential: Disease X

P Lawrence, M Heung, J Nave, C Henkel… - Current Opinion in …, 2023 - Elsevier
Over the last decade, the emergence of several zoonotic viruses has demonstrated that
previously unknown or neglected pathogens have the potential to cause epidemics and …

[HTML][HTML] SARS-CoV-2 shedding and evolution in immunocompromised hosts during the Omicron period: a multicenter prospective analysis

Z Raglow, D Surie, JD Chappell, Y Zhu, ET Martin… - medRxiv, 2023 - ncbi.nlm.nih.gov
Background: Prolonged SARS-CoV-2 infections in immunocompromised hosts may predict
or source the emergence of highly mutated variants. The types of immunosuppression …

Generation and functional analysis of defective viral genomes during SARS-CoV-2 infection

T Zhou, NJ Gilliam, S Li, S Spandau, RM Osborn… - Mbio, 2023 - Am Soc Microbiol
Defective viral genomes (DVGs) have been identified in many RNA viruses as a major factor
influencing antiviral immune response and viral pathogenesis. However, the generation and …

SARS‐CoV‐2 in digital era: Diagnostic techniques and importance of nucleic acid quantification with digital PCRs

N Aravind Kumar, S Aradhana, Harleen… - Reviews in Medical …, 2023 - Wiley Online Library
Studies related to clinical diagnosis and research of SARS‐CoV‐2 are important in the
current pandemic era. Although molecular biology has emphasised the importance of …

Cell cycle block by p53 activation reduces SARS-CoV-2 release in infected alveolar basal epithelial A549-hACE2 cells

G Lodi, V Gentili, F Casciano, A Romani… - Frontiers in …, 2022 - frontiersin.org
SARS-CoV viruses have been shown to downregulate cellular events that control antiviral
defenses. They adopt several strategies to silence p53, key molecule for cell homeostasis …

Integration of Omics Data and Network Models to Unveil Negative Aspects of SARS-CoV-2, from Pathogenic Mechanisms to Drug Repurposing

L Bernardo, A Lomagno, PL Mauri, D Di Silvestre - Biology, 2023 - mdpi.com
Simple Summary SARS-CoV-2 caused the COVID-19 health emergency, affecting millions
of people worldwide. Samples collected from hospitalized or dead patients from the early …

Web resources for SARS-CoV-2 genomic database, annotation, analysis and variant tracking

Y Cheng, C Ji, HY Zhou, H Zheng, A Wu - Viruses, 2023 - mdpi.com
The SARS-CoV-2 genomic data continue to grow, providing valuable information for
researchers and public health officials. Genomic analysis of these data sheds light on the …

Traceability of SARS‐CoV‐2 transmission through quasispecies analysis

S Messali, A Rondina, M Giovanetti… - Journal of Medical …, 2023 - Wiley Online Library
During COVID‐19 pandemic, consensus genomic sequences were used for rapidly monitor
the spread of the virus worldwide. However, less attention was paid to intrahost genetic …