The many facets of erythropoietin physiologic and metabolic response
S Suresh, PK Rajvanshi, CT Noguchi - Frontiers in physiology, 2020 - frontiersin.org
In mammals, erythropoietin (EPO), produced in the kidney, is essential for bone marrow
erythropoiesis, and hypoxia induction of EPO production provides for the important …
erythropoiesis, and hypoxia induction of EPO production provides for the important …
Erythropoietin in bone–controversies and consensus
Erythropoietin (Epo) is the main hormone that regulates the production of red blood cells
(hematopoiesis), by stimulating their progenitors. Beyond this vital function, several …
(hematopoiesis), by stimulating their progenitors. Beyond this vital function, several …
Erythropoietin directly stimulates osteoclast precursors and induces bone loss
S Hiram‐Bab, T Liron, N Deshet‐Unger… - The FASEB …, 2015 - Wiley Online Library
Erythropoietin (EPO) primarily regulates red blood cell formation, and EPO serum levels are
increased on hypoxic stress (eg, anemia and altitude). In addition to anemia, recent …
increased on hypoxic stress (eg, anemia and altitude). In addition to anemia, recent …
Erythropoietin promotes bone formation through EphrinB2/EphB4 signaling
Recent studies have demonstrated that erythropoietin (EPO) has extensive
nonhematopoietic biological functions. However, little is known about how EPO regulates …
nonhematopoietic biological functions. However, little is known about how EPO regulates …
Biomimetic UHMWPE/HA scaffolds with rhBMP-2 and erythropoietin for reconstructive surgery
F Senatov, G Amanbek, P Orlova, M Bartov… - Materials Science and …, 2020 - Elsevier
A promising direction for the replacement of expanded bone defects is the development of
bioimplants based on synthetic biocompatible materials impregnated with growth factors that …
bioimplants based on synthetic biocompatible materials impregnated with growth factors that …
Epo/EpoR signaling in osteoprogenitor cells is essential for bone homeostasis and Epo-induced bone loss
High erythropoietin (Epo) levels are detrimental to bone health in adult organisms. Adult
mice receiving high doses of Epo lose bone mass due to suppressed bone formation and …
mice receiving high doses of Epo lose bone mass due to suppressed bone formation and …
Investigation of cell‐free poly lactic acid/nanoclay scaffolds prepared via thermally induced phase separation technique containing hydroxyapatite nanocarriers of …
The use of cell‐free scaffolds containing bioactive molecules having a controlled released
pattern has been proposed as a promising approach in field of tissue engineering. This …
pattern has been proposed as a promising approach in field of tissue engineering. This …
Effects of erythropoietin on osteoblast in the tooth extraction socket in mice periodontitis model
JE Bae, SM Hwang, YP Aryal, TY Kim, WJ Sohn… - Frontiers in …, 2022 - frontiersin.org
Periodontitis is an excessive inflammatory event in tooth-supporting tissues and can cause
tooth loss. We used erythropoietin (EPO), which has been reported to play an important role …
tooth loss. We used erythropoietin (EPO), which has been reported to play an important role …
High plasma erythropoietin predicts incident fractures in elderly men with normal renal function: the MrOS Sweden Cohort
HL Kristjansdottir, C Lewerin, UH Lerner… - Journal of Bone and …, 2020 - academic.oup.com
Preclinical studies on the role of erythropoietin (EPO) in bone metabolism are contradictory.
Regeneration models indicate an anabolic effect on bone healing, whereas models on …
Regeneration models indicate an anabolic effect on bone healing, whereas models on …
Erythropoietin enhances bone repair effects via the hypoxia-inducible factor signal pathway in glucocorticoid-induced osteonecrosis of the femoral head
D Li, Q Hu, G Tan, X Xie, Z Yang, P Kang - The American Journal of the …, 2018 - Elsevier
Background This study aimed to determine whether erythropoietin could repair
glucocorticoid-induced osteonecrosis of the femoral head after the systemic or local …
glucocorticoid-induced osteonecrosis of the femoral head after the systemic or local …