Anxiety disorders are the most common mental disorders and are often chronic and
disabling. Although exposure-based treatments are effective, a substantial number of …

Research in nonhuman animals suggests that reactivation can induce a transient, unstable
state in a previously consolidated memory, during which the memory can be disrupted or …

Experimental research on emotional memory reconsolidation interference, or the induction
of amnesia for previously established emotional memory, has a long tradition, but the …

Behavioral strategies to enhance fear extinction may provide powerful clinical applications
to further maximize the efficacy of exposure-based interventions. However, future …

Behavioral neuroscience has greatly informed how we understand the formation,
persistence, and plasticity of memory. Research has demonstrated that memory reactivation …

In this article, the authors seek to summarize the core mechanisms of cognitive behavioral
therapies (CBTs). Core mechanisms of CBT include the specific psychological factors …

Background Consolidated memories can undergo enduring modification through retrieval-
dependent treatments that modulate reconsolidation. This represents a potentially …

Recent research suggests that the mere act of retrieving a memory can temporarily make
that memory vulnerable to disruption. This process of “reconsolidation” will typically …

Memory retrieval induces a transient period of increased transcriptional and translational
regulation in neurons called reconsolidation, which is regulated by the protein kinase B …

Labilization-reconsolidation, which relies on retrieval, has been considered an opportunity
to attenuate the negative aspects of traumatic memories. A therapeutic strategy based on …