PURPOSE To provide guidance on the use of opioids to manage pain from cancer or cancer
treatment in adults. METHODS A systematic review of the literature identified systematic …

Use of opioids for the treatment of pain is necessary for the majority of patients with
advanced cancer, however its use has become challenging in the face of the opioid …

Importance One of the main aims of research on nonmedical opioid use (NMOU) is to
reduce the frequency of NMOU behaviors through interventions such as universal …

Background: The opioid use disorder is an international public health problem. Over the past
20 years it has been the subject of numerous publications concerning patients treated for …

Simple Summary The health care delivery model has dramatically changed due to the
emergence of the global pandemic coronavirus disease (COVID-19). This can be seen in …

Background Patients with cancer may be at risk of high opioid use due to physical and
psychosocial factors, although little data exist to inform providers and policymakers. Our aim …

Rationale: Tumor ablation can cause severe pain to patients, but there is no satisfactory
means of analgesia available. In addition, recurrence of residual tumors due to incomplete …

Opinion statement Opioids are the gold standard for the treatment of cancer-related pain.
Preclinical studies have associated opioids with cancer progression and overall survival. In …

Opinion statement Preventing depression in cancer patients on long-term opioid therapy
should begin with depression screening before opioid initiation and repeated screening …

Opioid analgesic tolerance, a root cause of opioid overdose and misuse, can develop
through an associative learning. Despite intensive research, the locus and central pathway …