The mass production of redundant, misleading, and conflicted systematic reviews and meta‐analyses

JPA Ioannidis - The Milbank Quarterly, 2016 - Wiley Online Library
Policy Points: Currently, there is massive production of unnecessary, misleading, and
conflicted systematic reviews and meta‐analyses. Instead of promoting evidence‐based …

The influence of industry sponsorship on the research agenda: a scoping review

A Fabbri, A Lai, Q Grundy… - American journal of …, 2018 - ajph.aphapublications.org
Background. Corporate interests have the potential to influence public debate and
policymaking by influencing the research agenda, namely the initial step in conducting …

Preferred reporting items for overviews of systematic reviews including harms checklist: a pilot tool to be used for balanced reporting of benefits and harms

KI Bougioukas, A Liakos, A Tsapas, E Ntzani… - Journal of clinical …, 2018 - Elsevier
Objectives An overview of systematic reviews (OoSRs) is a study designed to synthesize
multiple evidence from existing systematic reviews on a specific domain. The aim of this …

Overlapping meta-analyses on the same topic: survey of published studies

Objective To assess how common it is to have multiple overlapping meta-analyses of
randomized trials published on the same topic. Design Survey of published meta-analyses …

Effectiveness of acupuncture and related therapies for palliative care of cancer: overview of systematic reviews

X Wu, VCH Chung, EP Hui, ETC Ziea, BFL Ng… - Scientific reports, 2015 - nature.com
Acupuncture and related therapies such as moxibustion and transcutaneous electrical nerve
stimulation are often used to manage cancer-related symptoms, but their effectiveness and …

Meta-analyses with industry involvement are massively published and report no caveats for antidepressants

S Ebrahim, S Bance, A Athale, C Malachowski… - Journal of clinical …, 2016 - Elsevier
Objectives To identify the impact of industry involvement in the publication and interpretation
of meta-analyses of antidepressant trials in depression. Study Design and Setting Using …

Wasted research when systematic reviews fail to provide a complete and up-to-date evidence synthesis: the example of lung cancer

P Créquit, L Trinquart, A Yavchitz, P Ravaud - BMC medicine, 2016 - Springer
Background Multiple treatments are frequently available for a given condition, and clinicians
and patients need a comprehensive, up-to-date synthesis of evidence for all competing …

Does type of funding affect reporting in network meta-analysis? A scoping review of network meta-analyses

AA Veroniki, EKC Wong, C Lunny… - Systematic …, 2023 - Springer
Background Evidence has shown that private industry-sponsored randomized controlled
trials (RCTs) and meta-analyses are more likely to report intervention-favourable results …

How good is “evidence” from clinical studies of drug effects and why might such evidence fail in the prediction of the clinical utility of drugs?

H Naci, JPA Ioannidis - Annual review of pharmacology and …, 2015 - annualreviews.org
Promising evidence from clinical studies of drug effects does not always translate to
improvements in patient outcomes. In this review, we discuss why early evidence is often ill …

Future of evidence ecosystem series: 1. Introduction evidence synthesis ecosystem needs dramatic change

I Boutron, P Créquit, H Williams, J Meerpohl… - Journal of Clinical …, 2020 - Elsevier
Objectives This article presents why the planning, conduct, and reporting of systematic
reviews and meta-analyses of therapeutic interventions are suboptimal. Study Design and …