Teeth are found in almost all vertebrates, and they therefore provide a general paradigm for
the study of epithelial organ development and evolution. Here, we review the developmental …

Mammalian teeth develop from oral ectoderm and neural crest derived mesenchyme. The
first morphological sign is the primary dental lamina forming as a thickening of oral …

The continuously growing mouse incisor serves as a valuable model to study stem cell
regulation during organ renewal. Epithelial stem cells are localized in the proximal end of …

Tooth root development begins after the completion of crown formation in mammals.
Previous studies have shown that Hertwig's epithelial root sheath (HERS) plays an important …

Developmental abnormalities of craniofacial structures and teeth often occur sporadically
and the underlying genetic defects are not well understood, in part due to unknown gene …

Teeth are unique to vertebrates and have played a central role in their evolution. The
molecular pathways and morphogenetic processes involved in tooth development have …

Not only are teeth essential for mastication, but also missing teeth are considered a social
handicap due to speech and aesthetic problems, with a resulting high impact on emotional …

This paper reviews the current understanding of the progressive changes mediating dental
epithelial histogenesis as a basis for future collaborative studies. Tooth development …

Rodent incisors are capable of growing continuously and the renewal of dental epithelium
giving rise to enamel-forming ameloblasts and dental mesenchyme giving rise to dentin …

In mouse tooth development, the roots of the first lower molar develop after crown formation
to form 2 cylindrical roots by post-natal day 5. This study compared the morphogenesis and …