Influenza virus and SARS-CoV-2: pathogenesis and host responses in the respiratory tract
T Flerlage, DF Boyd, V Meliopoulos… - Nature Reviews …, 2021 - nature.com
Influenza viruses cause annual epidemics and occasional pandemics of respiratory tract
infections that produce a wide spectrum of clinical disease severity in humans. The novel …
infections that produce a wide spectrum of clinical disease severity in humans. The novel …
B cells, plasma cells and antibody repertoires in the tumour microenvironment
GV Sharonov, EO Serebrovskaya… - Nature Reviews …, 2020 - nature.com
Recent data show that B cells and plasma cells located in tumours or in tumour-draining
lymph nodes can have important roles in shaping antitumour immune responses. In tumour …
lymph nodes can have important roles in shaping antitumour immune responses. In tumour …
[PDF][PDF] COVID-19 immune features revealed by a large-scale single-cell transcriptome atlas
A dysfunctional immune response in coronavirus disease 2019 (COVID-19) patients is a
recurrent theme impacting symptoms and mortality, yet a detailed understanding of pertinent …
recurrent theme impacting symptoms and mortality, yet a detailed understanding of pertinent …
Immunosenescence and human vaccine immune responses
SN Crooke, IG Ovsyannikova, GA Poland… - Immunity & …, 2019 - Springer
The age-related dysregulation and decline of the immune system—collectively termed
“immunosenescence”—has been generally associated with an increased susceptibility to …
“immunosenescence”—has been generally associated with an increased susceptibility to …
[HTML][HTML] Remodeling of the immune response with aging: immunosenescence and its potential impact on COVID-19 immune response
Elderly individuals are the most susceptible to an aggressive form of coronavirus disease
(COVID-19), caused by SARS-CoV-2. The remodeling of immune response that is observed …
(COVID-19), caused by SARS-CoV-2. The remodeling of immune response that is observed …
[HTML][HTML] Race and ethnicity, gender, and age on perceived threats and fear of COVID-19: Evidence from two national data sources
Previous studies find preventative behaviors designed to reduce the number of infections
during emerging disease outbreaks are associated with perceived risk of disease …
during emerging disease outbreaks are associated with perceived risk of disease …
[HTML][HTML] The evolution of seasonal influenza viruses
VN Petrova, CA Russell - Nature Reviews Microbiology, 2018 - nature.com
Despite decades of surveillance and pharmaceutical and non-pharmaceutical interventions,
seasonal influenza viruses continue to cause epidemics around the world each year. The …
seasonal influenza viruses continue to cause epidemics around the world each year. The …
Evolution of the immune system in humans from infancy to old age
AK Simon, GA Hollander… - Proceedings of the …, 2015 - royalsocietypublishing.org
This article reviews the development of the immune response through neonatal, infant and
adult life, including pregnancy, ending with the decline in old age. A picture emerges of a …
adult life, including pregnancy, ending with the decline in old age. A picture emerges of a …
Error filtering, pair assembly and error correction for next-generation sequencing reads
RC Edgar, H Flyvbjerg - Bioinformatics, 2015 - academic.oup.com
Motivation: Next-generation sequencing produces vast amounts of data with errors that are
difficult to distinguish from true biological variation when coverage is low. Results: We …
difficult to distinguish from true biological variation when coverage is low. Results: We …