[HTML][HTML] Alveolar type II epithelial cell FASN maintains lipid homeostasis in experimental COPD

LC Fan, K McConn, M Plataki, S Kenny, NC Williams… - JCI insight, 2023 - ncbi.nlm.nih.gov
Alveolar epithelial type II (AEC2) cells strictly regulate lipid metabolism to maintain surfactant
synthesis. Loss of AEC2 cell function and surfactant production are implicated in the …

Molecular Impact of Conventional and Electronic Cigarettes on Pulmonary Surfactant

ML Garavaglia, F Bodega, C Porta, A Milzani… - International Journal of …, 2023 - mdpi.com
The alveolar epithelium is covered by a non-cellular layer consisting of an aqueous
hypophase topped by pulmonary surfactant, a lipo-protein mixture with surface-active …

Revisiting the role of phospholipases in alzheimer's: crosstalk with processed food

A Pethe, S Joshi, T Ali Dar… - Critical Reviews in Food …, 2024 - Taylor & Francis
Phospholipases such as phospholipase-A, phospholipase-B, phospholipase-C and
phospholipase-D are important functional enzymes of the cell membrane responsible for a …

Loss of TIPE3 reduced the proliferation, survival and migration of lung cancer cells through inactivation of Akt/mTOR, NF-κB, and STAT-3 signaling cascades

D Bordoloi, C Harsha, G Padmavathi, K Banik, BL Sailo… - Life Sciences, 2022 - Elsevier
Lung cancer is the foremost cause of cancer related mortality among men and one of the
most fatal cancers among women. Notably, the 5-year survival rate of lung cancer is very …

Nicotiana alkaloids-intervened phospholipid ozonolysis at the air-water interface

Y Liu, G Kan, Y Wang, Y Chen, Y Niu, J He, Y Ju… - Science of The Total …, 2024 - Elsevier
Cigarette nicotiana alkaloids associated with lung and cardiovascular diseases attack
enormous attention. However, the mechanism at the molecular level between nicotiana …

Betulinic acid abates N‐nitrosodimethylamine‐induced changes in lipid metabolism, oxidative stress, and inflammation in the liver and kidney of Wistar rats

GE Adeleke, OA Adaramoye - Journal of Biochemical and …, 2021 - Wiley Online Library
N‐nitrosamines have been linked with cancer in humans due to their presence in drinking
water and diets. This study evaluated the role of betulinic acid (BA) in abating oxidative …

Plasma lipid profiling identifies phosphatidylcholine 34: 3 and triglyceride 52: 3 as potential markers associated with disease severity and oxidative status in chronic …

A Ben Anes, H Ben Nasr, Z Tabka, O Tabka, M Zaouali… - Lung, 2022 - Springer
Purpose To identify plasma alterations in lipid species in patients with chronic obstructive
pulmonary disease (COPD), as well as, relationships with smoking status, oxidative and …

Inflection of Akt/mTOR/STAT-3 cascade in TNF-α induced protein 8 mediated human lung carcinogenesis

D Bordoloi, K Banik, R Vikkurthi, KK Thakur… - Life sciences, 2020 - Elsevier
Lung cancer is the leading cause of cancer-related death across the globe. Despite the
marked advances in detection and therapeutic approaches, management of lung cancer …

Intake of tobacco nitrosamines of smokers in various provinces of China and their cancer risk: A meta-analysis

X Li, Z Ye, J Wang, P Lin, X Zhang, S Xie… - Journal of Environmental …, 2024 - Elsevier
Nitrosamines are a class of carcinogens which have been detected widely in food, water,
some pharmaceuticals as well as tobacco. The objectives of this paper include reviewing the …

Cigarette smoke-induced alterations in frontal white matter lipid profiles demonstrated by MALDI-imaging mass spectrometry: Relevance to Alzheimer's disease

K Nunez, J Kay, A Krotow, M Tong… - Journal of …, 2016 - content.iospress.com
Background: Meta-analysis has shown that smokers have significantly increased risks for
Alzheimer's disease (AD), and neuroimaging studies showed that smoking alters white …