Crosstalk between oxidative stress and inflammatory liver injury in the pathogenesis of alcoholic liver disease
Alcoholic liver disease (ALD) is characterized by the injury, inflammation, and scarring in the
liver owing to excessive alcohol consumption. Currently, ALD is a leading cause for liver …
liver owing to excessive alcohol consumption. Currently, ALD is a leading cause for liver …
Fatty liver disease-alcoholic and non-alcoholic: similar but different
SDH Malnick, P Alin, M Somin… - International Journal of …, 2022 - mdpi.com
In alcohol-induced liver disease (ALD) and in non-alcoholic fatty liver disease (NAFLD),
there are abnormal accumulations of fat in the liver. This phenomenon may be related to …
there are abnormal accumulations of fat in the liver. This phenomenon may be related to …
[HTML][HTML] Growing burden of alcoholic liver disease in China: a review
WJ Wang, P Xiao, HQ Xu, JQ Niu… - World Journal of …, 2019 - ncbi.nlm.nih.gov
Explosive economic growth and increasing social openness in China over the last 30 years
have significantly boosted alcohol consumption, and consequently, the incidence of …
have significantly boosted alcohol consumption, and consequently, the incidence of …
Autophagy, oxidative stress, and alcoholic liver disease: a systematic review and potential clinical applications
D Salete-Granado, C Carbonell, D Puertas-Miranda… - Antioxidants, 2023 - mdpi.com
Ethanol consumption triggers oxidative stress by generating reactive oxygen species (ROS)
through its metabolites. This process leads to steatosis and liver inflammation, which are …
through its metabolites. This process leads to steatosis and liver inflammation, which are …
Stress-and drug-induced neuroimmune signaling as a therapeutic target for comorbid anxiety and substance use disorders
Stress and substance use disorders remain two of the most highly prevalent psychiatric
conditions and are often comorbid. While individually these conditions have a debilitating …
conditions and are often comorbid. While individually these conditions have a debilitating …
Current therapeutic options and potential of mesenchymal stem cell therapy for alcoholic liver disease
J Han, C Lee, J Hur, Y Jung - Cells, 2022 - mdpi.com
Alcoholic liver disease (ALD) is a globally prevalent chronic liver disease caused by chronic
or binge consumption of alcohol. The therapeutic efficiency of current therapies for ALD is …
or binge consumption of alcohol. The therapeutic efficiency of current therapies for ALD is …
N acetylcysteine in the treatment of alcohol use disorder: a randomized, double-blind, placebo-controlled trial
N-acetyl cysteine (NAC) is a potent antioxidant that modulates glutamatergic signalling
which is thought to play a role in alcohol use disorder (AUD). There have been no clinical …
which is thought to play a role in alcohol use disorder (AUD). There have been no clinical …
Alcohol and the mechanisms of liver disease
M Chen, W Zhong, W Xu - Journal of Gastroenterology and …, 2023 - Wiley Online Library
Alcoholic liver disease (ALD), which is a leading cause of morbidity and mortality worldwide,
covers a large spectrum of liver injuries ranging from simple steatosis to steatohepatitis …
covers a large spectrum of liver injuries ranging from simple steatosis to steatohepatitis …
New approved and emerging pharmacological approaches to alcohol use disorder: a review of clinical studies
Abstract introduction: The number of medications approved for AUD is small and they
generally have limited efficacy. We need new pharmacotherapies for the management of …
generally have limited efficacy. We need new pharmacotherapies for the management of …
Medication development for alcohol use disorder: a focus on clinical studies
L Leggio, DE Falk, ML Ryan, J Fertig… - Substance Use Disorders …, 2020 - Springer
Compared to other medical disorders, including other brain diseases, the number of
medications approved for alcohol use disorder (AUD) is very small. Disulfiram, naltrexone …
medications approved for alcohol use disorder (AUD) is very small. Disulfiram, naltrexone …