Alcoholic liver disease (ALD) is characterized by the injury, inflammation, and scarring in the
liver owing to excessive alcohol consumption. Currently, ALD is a leading cause for liver …

In alcohol-induced liver disease (ALD) and in non-alcoholic fatty liver disease (NAFLD),
there are abnormal accumulations of fat in the liver. This phenomenon may be related to …

Explosive economic growth and increasing social openness in China over the last 30 years
have significantly boosted alcohol consumption, and consequently, the incidence of …

Ethanol consumption triggers oxidative stress by generating reactive oxygen species (ROS)
through its metabolites. This process leads to steatosis and liver inflammation, which are …

Stress and substance use disorders remain two of the most highly prevalent psychiatric
conditions and are often comorbid. While individually these conditions have a debilitating …

Alcoholic liver disease (ALD) is a globally prevalent chronic liver disease caused by chronic
or binge consumption of alcohol. The therapeutic efficiency of current therapies for ALD is …

N-acetyl cysteine (NAC) is a potent antioxidant that modulates glutamatergic signalling
which is thought to play a role in alcohol use disorder (AUD). There have been no clinical …

Alcoholic liver disease (ALD), which is a leading cause of morbidity and mortality worldwide,
covers a large spectrum of liver injuries ranging from simple steatosis to steatohepatitis …

Abstract introduction: The number of medications approved for AUD is small and they
generally have limited efficacy. We need new pharmacotherapies for the management of …

Compared to other medical disorders, including other brain diseases, the number of
medications approved for alcohol use disorder (AUD) is very small. Disulfiram, naltrexone …