Human monocyte subsets and phenotypes in major chronic inflammatory diseases
Human monocytes are divided in three major populations; classical (CD14+ CD16−), non-
classical (CD14dimCD16+), and intermediate (CD14+ CD16+). Each of these subsets is …
classical (CD14dimCD16+), and intermediate (CD14+ CD16+). Each of these subsets is …
The impact of ageing on monocytes and macrophages
RPH De Maeyer, ES Chambers - Immunology letters, 2021 - Elsevier
Ageing is a global burden. Increasing age is associated with increased incidence of
infections and cancer and decreased vaccine efficacy. This increased morbidity observed …
infections and cancer and decreased vaccine efficacy. This increased morbidity observed …
[HTML][HTML] Persistence of SARS CoV-2 S1 protein in CD16+ monocytes in post-acute sequelae of COVID-19 (PASC) up to 15 months post-infection
BK Patterson, EB Francisco, R Yogendra… - Frontiers in …, 2022 - frontiersin.org
The recent COVID-19 pandemic is a treatment challenge in the acute infection stage but the
recognition of chronic COVID-19 symptoms termed post-acute sequelae SARS-CoV-2 …
recognition of chronic COVID-19 symptoms termed post-acute sequelae SARS-CoV-2 …
A pan-cancer blueprint of the heterogeneous tumor microenvironment revealed by single-cell profiling
The stromal compartment of the tumor microenvironment consists of a heterogeneous set of
tissue-resident and tumor-infiltrating cells, which are profoundly moulded by cancer cells. An …
tissue-resident and tumor-infiltrating cells, which are profoundly moulded by cancer cells. An …
DoubletFinder: doublet detection in single-cell RNA sequencing data using artificial nearest neighbors
Single-cell RNA sequencing (scRNA-seq) data are commonly affected by technical artifacts
known as" doublets," which limit cell throughput and lead to spurious biological conclusions …
known as" doublets," which limit cell throughput and lead to spurious biological conclusions …
From monocytes to M1/M2 macrophages: phenotypical vs. functional differentiation
P Italiani, D Boraschi - Frontiers in immunology, 2014 - frontiersin.org
Studies on monocyte and macrophage biology and differentiation have revealed the
pleiotropic activities of these cells. Macrophages are tissue sentinels that maintain tissue …
pleiotropic activities of these cells. Macrophages are tissue sentinels that maintain tissue …
[HTML][HTML] Phenotype, function, and differentiation potential of human monocyte subsets
LB Boyette, C Macedo, K Hadi, BD Elinoff, JT Walters… - PloS one, 2017 - journals.plos.org
Human monocytes have been grouped into classical (CD14++ CD16−), non-classical
(CD14dimCD16++), and intermediate (CD14++ CD16+) subsets. Documentation of normal …
(CD14dimCD16++), and intermediate (CD14++ CD16+) subsets. Documentation of normal …
Monocytes in rheumatoid arthritis: Circulating precursors of macrophages and osteoclasts and, their heterogeneity and plasticity role in RA pathogenesis
AK Rana, Y Li, Q Dang, F Yang - International immunopharmacology, 2018 - Elsevier
Rheumatoid arthritis (RA) is a chronic systemic, autoimmune and inflammatory disease
represented as synovitis, pannus formation, adjacent bone erosions, and joint destruction …
represented as synovitis, pannus formation, adjacent bone erosions, and joint destruction …
Non-classical monocytes display inflammatory features: validation in sepsis and systemic lupus erythematous
R Mukherjee, P Kanti Barman, P Kumar Thatoi… - Scientific reports, 2015 - nature.com
Given the importance of monocytes in pathogenesis of infectious and other inflammatory
disorders, delineating functional and phenotypic characterization of monocyte subsets has …
disorders, delineating functional and phenotypic characterization of monocyte subsets has …
Origin of monocytes and macrophages in a committed progenitor
J Hettinger, DM Richards, J Hansson, MM Barra… - Nature …, 2013 - nature.com
Monocytes, macrophages and dendritic cells (DCs) are developmentally related regulators
of the immune system that share the monocyte-macrophage DC progenitor (MDP) as a …
of the immune system that share the monocyte-macrophage DC progenitor (MDP) as a …