Progress in deciphering trophoblast cell differentiation during human placentation
Z Xiao, L Yan, X Liang, H Wang - Current opinion in cell biology, 2020 - Elsevier
The maintenance of gestational well-being requires the proper development of both the
embryo and the placenta. Placental trophoblast cells are the major building blocks of the …
embryo and the placenta. Placental trophoblast cells are the major building blocks of the …
A proteomic profile of the healthy human placenta
Background The placenta remains one of the least studied organs within the human body.
Yet, placental dysfunction has been associated with various pregnancy complications …
Yet, placental dysfunction has been associated with various pregnancy complications …
Prediction of HELLP syndrome severity using machine learning algorithms—results from a retrospective study
M Melinte-Popescu, IA Vasilache, D Socolov… - Diagnostics, 2023 - mdpi.com
(1) Background: HELLP (hemolysis, elevated liver enzymes, and low platelets) syndrome is
a rare and life-threatening complication of preeclampsia. The aim of this study was to …
a rare and life-threatening complication of preeclampsia. The aim of this study was to …
Placental proteome in late-onset of fetal growth restriction
T Gęca, A Stupak, R Nawrot… - Molecular …, 2022 - spandidos-publications.com
Fetal growth restriction (FGR) occurs when the fetus does not reach its genetically
programmed intrauterine potential for growth and affects~ 5–10% of pregnancies. This …
programmed intrauterine potential for growth and affects~ 5–10% of pregnancies. This …
Predictive performance of machine learning-based methods for the prediction of preeclampsia—a prospective study
AS Melinte-Popescu, IA Vasilache, D Socolov… - Journal of Clinical …, 2023 - mdpi.com
(1) Background: Preeclampsia (PE) prediction in the first trimester of pregnancy is a
challenge for clinicians. The aim of this study was to evaluate and compare the predictive …
challenge for clinicians. The aim of this study was to evaluate and compare the predictive …
Human OMICs and computational biology research in Africa: current challenges and prospects
Following the publication of the first human genome, OMICs research, including genomics,
transcriptomics, proteomics, and metagenomics, has been on the rise. OMICs studies …
transcriptomics, proteomics, and metagenomics, has been on the rise. OMICs studies …
Hydration free energies and solvation structures with molecular density functional theory in the hypernetted chain approximation
S Luukkonen, M Levesque, L Belloni… - The Journal of Chemical …, 2020 - pubs.aip.org
The capability of molecular density functional theory in its lowest, second-order
approximation, equivalent to the hypernetted chain approximation in integral equations, to …
approximation, equivalent to the hypernetted chain approximation in integral equations, to …
Regulation of epigenetic modifications in the placenta during preeclampsia: PPARγ influences H3K4me3 and H3K9ac in extravillous trophoblast cells
S Meister, L Hahn, S Beyer, C Paul, S Mitter… - International journal of …, 2021 - mdpi.com
The aim of this study was to analyze the expression of peroxisome proliferator-activated
receptor γ (PPARγ) and retinoid X receptor α (RxRα), a binding heterodimer playing a …
receptor γ (PPARγ) and retinoid X receptor α (RxRα), a binding heterodimer playing a …
Accurate prediction of hydration free energies and solvation structures using molecular density functional theory with a simple bridge functional
D Borgis, S Luukkonen, L Belloni… - The Journal of Chemical …, 2021 - pubs.aip.org
This paper assesses the ability of molecular density functional theory to predict efficiently
and accurately the hydration free energies of molecular solutes and the surrounding …
and accurately the hydration free energies of molecular solutes and the surrounding …
Assessment of placental extracellular vesicles-associated Fas ligand and TNF-related apoptosis-inducing ligand in pregnancies complicated by early and late onset …
P Ayala-Ramírez, C Machuca-Acevedo… - Frontiers in …, 2021 - frontiersin.org
Preeclampsia (PE) is a hypertensive disorder that affects 2–8% of pregnancies and is one of
the main causes of fetal, neonatal, and maternal mortality and morbidity worldwide. Although …
the main causes of fetal, neonatal, and maternal mortality and morbidity worldwide. Although …