[HTML][HTML] HMGB family proteins: Potential biomarkers and mechanistic factors in cardiovascular diseases

X Zheng, J Lu, J Liu, L Zhou, Y He - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Cardiovascular disease (CVD) is the most fatal disease that causes sudden death, and
inflammation contributes substantially to its occurrence and progression. The prevalence of …

Exploring the biological roles of DHX36, a DNA/RNA G-quadruplex helicase, highlights functions in male infertility: A comprehensive review

L Fu, Q Wu, J Fu - International Journal of Biological Macromolecules, 2024 - Elsevier
It is estimated that 15% of couples at reproductive age worldwide suffer from infertility,
approximately 50% of cases are caused by male factors. Significant progress has been …

Bisphenols and perfluoroalkyls alter human stem cells integrity: A possible link with infertility

G Gaggi, A Di Credico, F Barbagallo, B Ghinassi… - Environmental …, 2023 - Elsevier
Bisphenols and Perfluoroalkyls are chemical compounds widely used in industry known to
be endocrine disruptors (EDs). Once ingested through contaminated aliments, they mimic …

Single-Cell Transcriptome Sequencing Reveals Molecular Expression Differences and Marker Genes in Testes during the Sexual Maturation of Mongolian Horses

Y Liu, M Du, X Li, L Zhang, B Zhao, N Wang… - Animals, 2024 - mdpi.com
Simple Summary The results of this research revealed significant differences in the tissue
morphology and gene expression profiles of Mongolian horses based on age. Specifically …

CCDC183 is essential for cytoplasmic invagination around the flagellum during spermiogenesis and male fertility

K Shimada, M Ikawa - Development, 2023 - journals.biologists.com
Sperm flagellum plays a crucial role in male fertility. Here, we generated Ccdc183 knockout
mice using the CRISPR/Cas9 system to reveal the protein function of the testis-specific …

Genome-wide DNA methylation changes in human spermatogenesis

LM Siebert-Kuss, V Dietrich, S Di Persio… - The American Journal of …, 2024 - cell.com
Sperm production and function require the correct establishment of DNA methylation
patterns in the germline. Here, we examined the genome-wide DNA methylation changes …

The conserved genetic program of male germ cells uncovers ancient regulators of human spermatogenesis

RB Correia, JM Almeida, MJ Wyrwoll, I Julca, D Sobral… - bioRxiv, 2022 - biorxiv.org
Germ cells provide the cellular basis for sexual reproduction in multicellular animals. In
males, germ cells differentiate into sperm, one of the most morphologically diverse …