[HTML][HTML] Mpox (formerly monkeypox): pathogenesis, prevention, and treatment

J Lu, H Xing, C Wang, M Tang, C Wu, F Ye… - … and Targeted Therapy, 2023 - nature.com
In 2022, a global outbreak of Mpox (formerly monkeypox) occurred in various countries
across Europe and America and rapidly spread to more than 100 countries and regions. The …

[HTML][HTML] Genistein is effective in inhibiting Orf virus infection in vitro by targeting viral RNA polymerase subunit RPO30 protein

P Lv, Z Fang, J Guan, L Lv, M Xu, X Liu, Z Li… - Frontiers in …, 2024 - frontiersin.org
Orf virus (ORFV), a typical member of the genus Parapoxvirus, Poxvirus family, causes a
contagious pustular dermatitis in sheep, goats, and humans. Poxviruses encode a …

Triple in Silico Targeting of IMPDH Enzyme and RNA-Dependent RNA Polymerase of Both SARS-CoV-2 and Rhizopus Oryzae

AS Hassan, AA Elfiky, AM Elgohary - Future Microbiology, 2024 - Taylor & Francis
Aim: Mucormycosis has been associated with SARS-CoV-2 infections during the last year.
The aim of this study was to triple-hit viral and fungal RNA-dependent RNA polymerases …

[HTML][HTML] Immunoinformatics and reverse vaccinology approach in designing a novel highly immunogenic multivalent peptide-based vaccine against the human …

A Choudhury, A Chandra, TM Dawoud… - Frontiers in Molecular …, 2023 - frontiersin.org
Background: Monkeypox is a highly infectious zoonotic disease, often resulting in
complications ranging from respiratory illnesses to vision loss. The escalating global …

Exploration of the in vitro Antiviral Effects and the Active Components of Changyanning Tablets Against Enterovirus 71

Q Ge, Z Zhang, Z Cao, D Wu, C Xu, J Yao… - Drug Design …, 2024 - Taylor & Francis
Purpose This study aims to investigate the in vitro antiviral effects of the aqueous solution of
Changyanning (CYN) tablets on Enterovirus 71 (EV71), and to analyze its active …

Sinefungin analogs targeting VP39 methyltransferase as potential anti-monkeypox therapeutics: a multi-step computational approach

AS Abouzied, B Huwaimel, S Alqarni, KM Younes… - Molecular Diversity, 2024 - Springer
The increasing spread of the Monkeypox virus (MPXV) presents a significant public health
challenge, emphasising the urgent requirement for effective treatments. Our study focuses …

Deciphering Poxvirus Strains: Feature-Driven classification of Monkeypox

D Mehul - … Fourth International Conference on Advances in …, 2024 - ieeexplore.ieee.org
This research outlines a method for monkeypox virus classification from images,
emphasizing the effective management of augmented datasets to ensure balanced class …