Abstract Three-dimensional (3D) stem cell culture systems have attracted considerable
attention as a way to better mimic the complex interactions between individual cells and the …

The nervous system is a crucial component of the body and damages to this system, either
by of injury or disease, can result in serious or potentially lethal consequences. Restoring …

Stem cells exist as normal cells in embryonic and adult tissues. In recent years, scientists
have spared efforts to determine the role of stem cells in treating many diseases. Stem cells …

The therapy of neural nerve injuries that involve the disruption of axonal pathways or axonal
tracts has taken a new dimension with the development of tissue engineering techniques …

Neural tissue engineering (NTE) has made remarkable strides in recent years and holds
great promise for treating several devastating neurological disorders. Selecting optimal …

At present, repair methods for peripheral nerve injury often fail to get satisfactory result.
Although various strategies have been adopted to investigate the microenvironment after …

Dental follicle cells (DFCs) are a group of mesenchymal progenitor cells surrounding the
tooth germ, responsible for cementum, periodontal ligament, and alveolar bone formation in …

Controlled drug delivery in the oral cavity poses challenges such as bacterial contamination,
saliva dilution, and inactivation by salivary enzymes upon ingestion. Microneedles offer a …

Background The damaged neuronal cells of adult mammalian lack the regenerative ability to
replace the neuronal connections. Periodontal ligament stem cells (PDLSCs) are the …

Orofacial soft tissue wounds caused by surgery for congenital defects, trauma, or disease
frequently occur leading to complications affecting patients' quality of life. Scarring and …