Proteins are the main source of drug targets and some of them possess therapeutic potential
themselves. Among them, membrane proteins constitute approximately 50% of the major …

Control of malaria is an important global health issue and there is still an urgent need for the
development of an effective prophylactic vaccine. Multiple studies have provided strong …

Intracellular malaria parasites grow in a vacuole delimited by the parasitophorous vacuolar
membrane (PVM). This membrane fulfils critical roles for survival of the parasite in its …

Intraerythrocytic malaria parasites reside within a parasitophorous vacuole membrane
(PVM) that closely overlays the parasite plasma membrane. Although the PVM is the site of …

During blood-stage development, malaria parasites are challenged with the detoxification of
enormous amounts of heme released during the proteolytic catabolism of erythrocytic …

Background: T cells are thought to play a major role in conferring immunity against malaria.
This study aimed to comprehensively define the breadth and specificity of the Plasmodium …

Plasmodium falciparum accounts for the majority of malaria deaths, due to pathology
provoked by the ability of infected erythrocytes to adhere to vascular endothelium within …

Plasmodium falciparum proteins involved in vascular endothelial cell adherence are
transported to the surface of infected erythrocytes. These proteins are exported through …

Intracellular Plasmodium parasites develop inside a parasitophorous vacuole (PV), a
specialised compartment enclosed by a membrane (PVM) that contains proteins of both host …

Malaria is an important infectious disease that continues to claim hundreds of thousands of
lives annually. The disease is caused by infection of host erythrocytes by apicomplexan …