Chronic urticaria (CU) is a mast cell-driven chronic inflammatory disease with a female
predominance. Since CU affects mostly females in reproductive age, pregnancy is an …

Pregnancy presents the maternal immune system with a unique immunological challenge
since it has to defend against pathogens while tolerating paternal allo-antigens expressed …

Few studies have been published focusing on the clinical features of new-onset systemic
lupus erythematosus (SLE) during pregnancy. This study examined the clinical …

Publisher Summary Epidemiology is the study of the distribution of illnesses and diseases
and the factors affecting their incidence and clinical course in the population. Systemic lupus …

Systemic autoimmune diseases such as lupus affect multiple organs, usually in a diverse
fashion where only certain organs are affected in individual patients. It is unclear whether …

Background. Systemic lupus erythematosus (SLE) is still treated with global
immunosuppressants with serious toxicities. We hypothesized that endogenous …

Natural killer T (NKT) cells represent a unique T cell lineage. The NKT cells bearing an
invariant TCR (iNKT cells) recognize a small variety of glycolipid antigens in the context of …

Neuroimmune-endocrine interactions seem to be central to the dialogue between the
mother and the growing embryo during normal pregnancy. A proinflammatory Th1 …

The outcome of pregnancy in systemic lupus erythematosus is still controversial. The
authors recently reported the disappearance of the manifestation of the skin disease but a …

Pregnancy modulates autoimmune diseases through diverse and still incompletely defined
mechanisms, in part operating at the decidua–placenta interface. To assess the …