Ceria‐based therapeutic antioxidants for biomedical applications
The growing interest in nanomedicine over the last 20 years has carved out a research field
called “nanocatalytic therapy,” where catalytic reactions mediated by nanomaterials are …
called “nanocatalytic therapy,” where catalytic reactions mediated by nanomaterials are …
Enzyme-mimetic antioxidant nanomaterials for ROS scavenging: Design, classification, and biological applications
Reactive oxygen species (ROS) perform vital functions in numerous life processes and
significantly affect physiological activities in different organ systems in the human body …
significantly affect physiological activities in different organ systems in the human body …
Redox homeostasis strategy for inflammatory macrophage reprogramming in rheumatoid arthritis based on ceria oxide nanozyme-complexed biopolymeric micelles
F Zhou, M Li, M Chen, M Chen, X Chen, Z Luo, K Cai… - ACS …, 2023 - ACS Publications
The synovial tissues under rheumatoid arthritis conditions are usually infiltrated by
inflammatory cells, particularly M1 macrophages with aberrant redox homeostasis, which …
inflammatory cells, particularly M1 macrophages with aberrant redox homeostasis, which …
Targeting endogenous reactive oxygen species removal and regulating regenerative microenvironment at annulus fibrosus defects promote tissue repair
F Han, Z Tu, Z Zhu, D Liu, Q Meng, Q Yu, Y Wang… - ACS …, 2023 - ACS Publications
The excessive reactive oxygen species (ROS) level, inflammation, and weak tissue
regeneration ability after annulus fibrosus (AF) injury constitute an unfavorable …
regeneration ability after annulus fibrosus (AF) injury constitute an unfavorable …
Hydrogel dressing integrating FAK inhibition and ROS scavenging for mechano-chemical treatment of atopic dermatitis
Atopic dermatitis (AD) is a chronic skin disease caused by skin immune dyshomeostasis and
accompanied by severe pruritus. Although oxidative stress and mechanical scratching can …
accompanied by severe pruritus. Although oxidative stress and mechanical scratching can …
ROS‐Scavenging Hydrogels Synergize with Neural Stem Cells to Enhance Spinal Cord Injury Repair via Regulating Microenvironment and Facilitating Nerve …
D Liu, G Lu, B Shi, H Ni, J Wang, Y Qiu… - Advanced …, 2023 - Wiley Online Library
Although stem cell‐based therapy is recognized as a promising therapeutic strategy for
spinal cord injury (SCI), its efficacy is greatly limited by local reactive oxygen species (ROS) …
spinal cord injury (SCI), its efficacy is greatly limited by local reactive oxygen species (ROS) …
Cerium dioxide nanozyme doped hybrid hydrogel with antioxidant and antibacterial abilities for promoting diabetic wound healing
S Zhao, J Ling, N Wang, X Ouyang - Chemical Engineering Journal, 2024 - Elsevier
Diabetic wounds are among the most severe chronic complications in patients with diabetes.
Owing to the detrimental effects of high glucose and high levels of reactive oxygen species …
Owing to the detrimental effects of high glucose and high levels of reactive oxygen species …
Hyaluronic acid‐based reactive oxygen species‐responsive multifunctional injectable hydrogel platform accelerating diabetic wound healing
C Shi, Y Zhang, G Wu, Z Zhu, H Zheng… - Advanced …, 2024 - Wiley Online Library
Diabetic wounds are more likely to develop into complex and severe chronic wounds. The
objective of this study is to develop and assess a reactive oxygen species (ROS)‐responsive …
objective of this study is to develop and assess a reactive oxygen species (ROS)‐responsive …
Orally administrated inflamed colon-targeted nanotherapeutics for inflammatory bowel disease treatment by oxidative stress level modulation in colitis
Inflammatory bowel disease (IBD) is characterized by an inappropriate and persistent
inflammatory immune response and is often accompanied by excessive reactive oxygen …
inflammatory immune response and is often accompanied by excessive reactive oxygen …
Adhesive composite hydrogel patch for sustained transdermal drug delivery to treat atopic dermatitis
YE Kim, HY Jung, N Park, J Kim - Chemistry of Materials, 2023 - ACS Publications
Atopic dermatitis (AD) is a common chronic inflammatory skin disease. Continuous
administration of steroids often causes undesired side effects; hence, drug delivery systems …
administration of steroids often causes undesired side effects; hence, drug delivery systems …