Central nervous system control of glucose homeostasis: a therapeutic target for type 2 diabetes?
Z Mirzadeh, CL Faber… - Annual review of …, 2022 - annualreviews.org
Historically, pancreatic islet beta cells have been viewed as principal regulators of glycemia,
with type 2 diabetes (T2D) resulting when insulin secretion fails to compensate for …
with type 2 diabetes (T2D) resulting when insulin secretion fails to compensate for …
[HTML][HTML] Realising the long-term promise of insulin therapy: the DCCT/EDIC study
DM Nathan - Diabetologia, 2021 - Springer
The introduction of insulin in the treatment of juvenile-onset, now type 1, diabetes mellitus
transformed a rapidly fatal disease into a chronic degenerative one. During the insulin …
transformed a rapidly fatal disease into a chronic degenerative one. During the insulin …
American Association of Clinical Endocrinology clinical practice guideline: developing a diabetes mellitus comprehensive care plan—2022 update
L Blonde, GE Umpierrez, SS Reddy, JB McGill… - Endocrine Practice, 2022 - Elsevier
Objective The objective of this clinical practice guideline is to provide updated and new
evidence-based recommendations for the comprehensive care of persons with diabetes …
evidence-based recommendations for the comprehensive care of persons with diabetes …
Real-time continuous glucose monitoring in adults with type 1 diabetes and impaired hypoglycaemia awareness or severe hypoglycaemia treated with multiple daily …
L Heinemann, G Freckmann, D Ehrmann… - The Lancet, 2018 - thelancet.com
Background The effectiveness of real-time continuous glucose monitoring (rtCGM) in
avoidance of hypoglycaemia among high-risk individuals with type 1 diabetes treated with …
avoidance of hypoglycaemia among high-risk individuals with type 1 diabetes treated with …
[HTML][HTML] A parallel randomised controlled trial of the Hypoglycaemia Awareness Restoration Programme for adults with type 1 diabetes and problematic …
SA Amiel, L Potts, K Goldsmith, P Jacob… - Nature …, 2022 - nature.com
Impaired awareness of hypoglycaemia (IAH) is a major risk for severe hypoglycaemia in
insulin treatment of type 1 diabetes (T1D). To explore the hypothesis that unhelpful health …
insulin treatment of type 1 diabetes (T1D). To explore the hypothesis that unhelpful health …
Efficacy and safety of suspend-before-low insulin pump technology in hypoglycaemia-prone adults with type 1 diabetes (SMILE): an open-label randomised controlled …
E Bosi, P Choudhary, HW De Valk… - The lancet Diabetes & …, 2019 - thelancet.com
Background Hypoglycaemia unawareness and severe hypoglycaemia can increase fear of
hypoglycaemia and the risk of subsequent hypoglycaemic events. We aimed to assess the …
hypoglycaemia and the risk of subsequent hypoglycaemic events. We aimed to assess the …
[HTML][HTML] Residual β cell function in long-term type 1 diabetes associates with reduced incidence of hypoglycemia
RA Gubitosi-Klug, BH Braffett, S Hitt… - The Journal of …, 2021 - Am Soc Clin Investig
BACKGROUND We investigated residual β cell function in Diabetes Control and
Complications Trial/Epidemiology of Diabetes Interventions and Complications …
Complications Trial/Epidemiology of Diabetes Interventions and Complications …
Improved glycemia with hybrid closed-loop versus continuous subcutaneous insulin infusion therapy: results from a randomized controlled trial
SK Garg, G Grunberger, R Weinstock… - Diabetes technology …, 2023 - liebertpub.com
Objective: To evaluate safety and effectiveness of MiniMed™ 670G hybrid closed loop
(HCL) in comparison with continuous subcutaneous insulin infusion (CSII) therapy for 6 …
(HCL) in comparison with continuous subcutaneous insulin infusion (CSII) therapy for 6 …
Hypoglycemia unawareness and autonomic dysfunction in diabetes: Lessons learned and roles of diabetes technologies
YK Lin, SJ Fisher, R Pop‐Busui - Journal of diabetes …, 2020 - Wiley Online Library
Impaired awareness of hypoglycemia (IAH) is a reduction in the ability to recognize low
blood glucose levels that would otherwise prompt an appropriate corrective therapy …
blood glucose levels that would otherwise prompt an appropriate corrective therapy …
Dual‐hormone artificial pancreas: benefits and limitations compared with single‐hormone systems
Technological advances have made the artificial pancreas a reality. This has the potential to
improve the lives of individuals with Type 1 diabetes by reducing the risk of hypoglycaemia …
improve the lives of individuals with Type 1 diabetes by reducing the risk of hypoglycaemia …