The view of CD4 T‐cell‐mediated immunity as a balance between distinct lineages of Th1
and Th2 cells has changed dramatically. Identification of the IL‐17 family of cytokines and of …

The clinical features, diagnostic challenges, neuroimaging appearance, therapeutic options,
and pathobiological research progress in childhood—and adolescent—onset multiple …

Objective To compare relapse rates in pediatric-onset multiple sclerosis (POMS) and adult-
onset multiple sclerosis (AOMS) over the first 6-years of disease. Methods Patients with …

Incomplete relapse recovery contributes to disability accrual and earlier onset of secondary
progressive multiple sclerosis. We sought to investigate the effect of age on relapse …

Elucidation of distinct T-cell subsets involved in multiple sclerosis immune-pathophysiology
continues to be of considerable interest since an ultimate goal is to more selectively target …

Objective The aim of this study was to examine the relative contributions of body mass index
(BMI) and pubertal measures for risk and age of onset of pediatric MS. Methods Case …

Abstract Purpose of Review Diagnostic criteria for pediatric-onset multiple sclerosis (POMS)
and related demyelinating disorders have been updated, neuroimaging studies have …

Elucidating pathophysiologic mechanisms underlying the spectrum of pediatric-onset CNS
demyelinating diseases, particularly those that may distinguish multiple sclerosis (MS) from …

Pediatric Central Nervous System Demyelinating Diseases : CONTINUUM: Lifelong
Learning in Neurology Account Register Activate Subscription Help Subscribe American …

Multiple sclerosis is being increasingly recognized and diagnosed in children. In the past
several years, advances have been made in diagnosing multiple sclerosis in children …