Targeting protein-protein interactions (PPIs) has been recently recognized as an emerging
therapeutic approach for several diseases. Up today, more than half a million PPI …

IL-15, a pleiotropic cytokine, stimulates generation of NK, NK-T, γδ, ILC1, and memory CD8
T cells. IL-15 disorders play pathogenetic roles in organ-specific autoimmune diseases …

Optoacoustic (photoacoustic) imaging offers unique opportunities for visualizing biological
function in vivo by achieving high-resolution images of optical contrast much deeper than …

Cytokines are a vital component of the immune system that controls the activation and
growth of blood cells. However, chronic overexpression of cytokines can trigger cellular …

Abstract Interleukin-15 (IL-15) is a member of the IL-2 family of cytokines, which use receptor
complexes containing the common gamma (γ c) chain for signaling. IL-15 plays important …

Anaplastic large cell lymphoma (ALCL), an aggressive CD30-positive T-cell lymphoma,
comprises systemic anaplastic lymphoma kinase (ALK)-positive, and ALK-negative, primary …

Abstract Purpose of Review The past decade in LGL leukemia research has seen increased
pairing of clinical data with molecular markers, shedding new insights on LGL leukemia …

Alopecia areata (AA) is an autoimmune condition that affects up to 2% of the general
population. Currently available treatment options for AA are of limited efficacy and can be …

Cytokines are pivotal mediators of cell communication in the tumor microenvironment.
Multiple cytokines are involved in the host antitumor response, but the production and …

Adult T-cell leukemia/lymphoma (ATLL) is an aggressive malignancy of CD4+ T
lymphocytes caused by human T lymphotropic virus type-1 (HTLV-1) infection. HTLV-1 was …