A novel definition and treatment of hyperinflammation in COVID-19 based on purinergic signalling
D Hasan, A Shono, CK van Kalken, PJ van der Spek… - Purinergic …, 2022 - Springer
Hyperinflammation plays an important role in severe and critical COVID-19. Using
inconsistent criteria, many researchers define hyperinflammation as a form of very severe …
inconsistent criteria, many researchers define hyperinflammation as a form of very severe …
Pharmacological Modulation and (Patho) Physiological Roles of TRPM4 Channel—Part 2: TRPM4 in Health and Disease
Transient receptor potential melastatin 4 (TRPM4) is a unique member of the TRPM protein
family and, similarly to TRPM5, is Ca2+ sensitive and permeable for monovalent but not …
family and, similarly to TRPM5, is Ca2+ sensitive and permeable for monovalent but not …
Lidocaine suppresses viability and migration of human breast cancer cells: TRPM7 as a target for some breast cancer cell lines
Simple Summary The local anesthetic lidocaine suppresses some cancer cell lines but the
mechanism is unclear. Melastatin-like transient receptor potential 7 (TRPM7) ion channels …
mechanism is unclear. Melastatin-like transient receptor potential 7 (TRPM7) ion channels …
[HTML][HTML] Medical perspective in testicular ischemia‑reperfusion injury
S Arena, R Iacona, P Antonuccio… - Experimental and …, 2017 - spandidos-publications.com
Testicular torsion or torsion of the spermatic cord is one of the most serious urological
conditions. It causes testicular injury, which potentially leads to male subfertility. The turning …
conditions. It causes testicular injury, which potentially leads to male subfertility. The turning …
Transient receptor potential melastatin 7 and their modulators
XY Cheng, SF Li, Y Chen, YJ Zhao, W Hu, C Lu… - European Journal of …, 2022 - Elsevier
TRPM (transient receptor potential melastatin) 7, a member of the TRPM subfamily, is a
nonselective cation channel located on the cell membrane that regulates mammalian cell …
nonselective cation channel located on the cell membrane that regulates mammalian cell …
Detrimental or beneficial: the role of TRPM2 in ischemia/reperfusion injury
K Zhan, P Yu, C Liu, J Luo, W Yang - Acta Pharmacologica Sinica, 2016 - nature.com
Abstract Ischemia/reperfusion (I/R) injury is the main cause of tissue damage and
dysfunction. I/R injury is characterized by Ca 2+ overload and production of reactive oxygen …
dysfunction. I/R injury is characterized by Ca 2+ overload and production of reactive oxygen …
Nickel (II) and cobalt (II) complexes of lidocaine: Synthesis, structure and comparative in vitro evaluations of biological perspectives
Metal complexes of the type [Ni (LC) 2 (X) 2], 1 and 2,[Co (LC) 2 (X) 2], 3 and 4 (LC:
lidocaine, X= dca (dicyanamide), 1 and 3, X= NCS−, 2 and 4) have been synthesized and …
lidocaine, X= dca (dicyanamide), 1 and 3, X= NCS−, 2 and 4) have been synthesized and …
Effects of amlodipine on ischaemia/reperfusion injury in the rat testis
The aim of this study was to examine the effects of amlodipine (AML) in rat testicular
torsion/detorsion damage. In this study, rats were divided into eight groups:(i) sham;(ii) …
torsion/detorsion damage. In this study, rats were divided into eight groups:(i) sham;(ii) …
Effects of lidocaine on random skin flap survival in rats
B Cao, L Wang, D Lin, L Cai, W Gao - Dermatologic Surgery, 2015 - journals.lww.com
Effects of Lidocaine on Random Skin Flap Survival in Rats : Dermatologic Surgery Effects of
Lidocaine on Random Skin Flap Survival in Rats : Dermatologic Surgery Log in or Register …
Lidocaine on Random Skin Flap Survival in Rats : Dermatologic Surgery Log in or Register …
[HTML][HTML] Over-activation of TRPM2 ion channel accelerates blood-spinal cord barrier destruction in diabetes combined with spinal cord injury rat
S Zhang, J Zhao, M Wu, Y Zhou, X Wu… - … Journal of Biological …, 2023 - ncbi.nlm.nih.gov
Spinal cord injury (SCI) is a devastating neurological disorder that often results in loss of
motor and sensory function. Diabetes facilitates the blood-spinal cord barrier (BSCB) …
motor and sensory function. Diabetes facilitates the blood-spinal cord barrier (BSCB) …