One could certainly highlight a conceptual resemblance between social interactions as the
basis of societies and civilizations and the ability of molecules to interact in a noncovalent …

Multivalency plays a major role in biological processes and particularly in the relationship
between pathogenic microorganisms and their host that involves protein–glycan recognition …

Chemical tools have proven indispensable for studies in glycobiology. Synthetic
oligosaccharides and glycoconjugates provide materials for correlating structure with …

Glycans are key participants in biological processes ranging from reproduction to cellular
communication to infection. Revealing glycan roles and the underlying molecular …

Nanotechnology, science, and engineering spearhead the 21st century revolution that is
leading to fundamental breakthroughs in the way materials, devices, and systems are …

Interfacial multivalent interactions at pathogen–cell interfaces can be competitively inhibited
by multivalent scaffolds that prevent pathogen adhesion to the cells during the initial stages …

Multivalent carbohydrates are currently produced in many forms ranging from dendrimers,
polymers, micelles, vesicles, nanoparticles to functionalized nanotubes, in order to enhance …

AB 5 toxins are important virulence factors for several major bacterial pathogens, including
Bordetella pertussis, Vibrio cholerae, Shigella dysenteriae and at least two distinct …

Shiga toxin has the potential to induce expression of inflammation-associated genes,
although the underlying mechanisms are not well understood. We examined the effects of …

AB5 toxins are produced by pathogenic bacteria and consist of enzymatic A subunits that
corrupt essential eukaryotic cell functions, and pentameric B subunits that mediate uptake …