We review the evolution and structure of members of the transforming growth factor β (TGF-
β) family, antagonistic or agonistic modulators, and receptors that regulate TGF-β signaling …

Bone morphogenetic proteins (BMPs) are secreted extracellular matrix (ECM)-associated
proteins that regulate a wide range of developmental processes, including limb and kidney …

Transforming growth factor-β (TGF-β) family members, which include TGF-βs, activins and
bone morphogenetic proteins, are pleiotropic cytokines that elicit cell type-specific effects in …

Hereditary hemorrhagic telangiectasia (HHT), the most common inherited vascular disorder,
is caused by mutations in genes involved in the transforming growth factor beta (TGF-β) …

The pleiotropic cytokine transforming growth factor-beta 1 (TGFβ1) plays pivotal roles in
different cell types, including immune cells such as T cells, monocytes/macrophages, and …

It is well established that control of vascular morphogenesis and homeostasis is regulated
by vascular endothelial growth factor (VEGF), fibroblast growth factor (FGF), Delta-like 4 …

Endoglin, a type-III accessory receptor for the Transforming Growth Factor (TGF)-β
superfamily pathway, is known for its crucial role during angiogenesis. Extensive work has …

Summary Endoglin (ENG)/CD105 is an essential endothelial cell co-receptor of the
transforming growth factor β (TGF-β) superfamily, mutated in hereditary hemorrhagic …

Endoglin (ENG) is a transmembrane glycoprotein expressed on endothelial cells that
functions as a co-receptor for several ligands of the transforming growth factor beta (TGF-β) …

Human endoglin is an RGD-containing transmembrane glycoprotein identified in vascular
endothelial cells. Although endoglin is essential for angiogenesis and its expression is up …