Liquid biopsy biomarkers in urine: a route towards molecular diagnosis and personalized medicine of bladder cancer

M Ferro, E La Civita, A Liotti, M Cennamo… - Journal of personalized …, 2021 - mdpi.com
Bladder cancer (BC) is characterized by high incidence and recurrence rates together with
genomic instability and elevated mutation degree. Currently, cystoscopy combined with …

Urinary microbiota and bladder cancer: A systematic review and a focus on uropathogens

A Yacouba, MT Alou, JC Lagier, G Dubourg… - Seminars in Cancer …, 2022 - Elsevier
The higher incidence of bladder cancer in men has long been attributed to environmental
factors, including smoking. The fact that the sex ratio of bladder cancer remains consistently …

[HTML][HTML] Microbiome Profiling in Bladder Cancer Patients Using the First-morning Urine Sample

C Nardelli, A Aveta, SD Pandolfo, L Tripodi… - European Urology Open …, 2024 - Elsevier
Background Several studies support the interplay between the urinary microbiome (ie,
urobiome) and bladder cancer (BCa). Specific urinary bacteria may be responsible for …

The bladder microbiome is associated with epithelial–mesenchymal transition in muscle invasive urothelial bladder carcinoma

WT Li, AS Iyangar, R Reddy, J Chakladar, V Bhargava… - Cancers, 2021 - mdpi.com
Simple Summary The abundance of microbial species residing within tumors is correlated to
cancer progression across many different cancers, including bladder cancer. However, links …

Bladder cancer-associated microbiota: Recent advances and future perspectives

W Zhang, F Yang, S Mao, R Wang, H Chen, Y Ran… - Heliyon, 2023 - cell.com
Recent evidence suggests that the human genitourinary microbiome plays a significant role
in mediating the development and progression of urological tumors, including bladder …

[HTML][HTML] The interplay between non-coding RNAs and Wnt/ß-catenin signaling pathway in urinary tract cancers: from tumorigenesis to metastasis

F Rahmani, P Safavi, A Fathollahpour, FTK Sabz… - EXCLI …, 2022 - ncbi.nlm.nih.gov
Non-coding RNAs (ncRNAs) are emerging as important regulators in various pathological
conditions including tumorigenesis, metastasis, and drug resistance in human cancers …

From mucosal infection to successful cancer immunotherapy

AG Goubet, M Rouanne, L Derosa, G Kroemer… - Nature Reviews …, 2023 - nature.com
The clinical management of advanced malignancies of the upper and lower urinary tract has
been revolutionized with the advent of immune checkpoint blockers (ICBs). ICBs reinstate or …

The Urinary Microbiome in Health and Disease: Relevance for Bladder Cancer

N Kustrimovic, G Bilato, L Mortara, D Baci - International Journal of …, 2024 - mdpi.com
Bladder cancer (BC) constitutes one of the most diagnosed types of cancer worldwide.
Advancements in and new methodologies for DNA sequencing, leading to high-throughput …

The link among microbiota, epigenetics, and disease development

A El-Sayed, L Aleya, M Kamel - Environmental Science and Pollution …, 2021 - Springer
The microbiome is a community of various microorganisms that inhabit or live on the skin of
humans/animals, sharing the body space with their hosts. It is a sort of complex ecosystem of …

Choice of 16S ribosomal RNA primers impacts male urinary microbiota profiling

V Heidrich, LT Inoue, PF Asprino, F Bettoni… - Frontiers in Cellular …, 2022 - frontiersin.org
Accessibility to next-generation sequencing (NGS) technologies has enabled the profiling of
microbial communities living in distinct habitats. 16S ribosomal RNA (rRNA) gene …