Insertion sequences
J Mahillon, M Chandler - Microbiology and molecular biology …, 1998 - Am Soc Microbiol
Insertion sequences (ISs) constitute an important component of most bacterial genomes.
Over 500 individual ISs have been described in the literature to date, and many more are …
Over 500 individual ISs have been described in the literature to date, and many more are …
DNA transposons: nature and applications in genomics
M Muñoz-López, JL García-Pérez - Current genomics, 2010 - ingentaconnect.com
Repeated DNA makes up a large fraction of a typical mammalian genome, and some
repetitive elements are able to move within the genome (transposons and retrotransposons) …
repetitive elements are able to move within the genome (transposons and retrotransposons) …
A genetic resource for rapid and comprehensive phenotype screening of nonessential Staphylococcus aureus genes
To enhance the research capabilities of investigators interested in Staphylococcus aureus,
the Nebraska Center for Staphylococcal Research (CSR) has generated a sequence …
the Nebraska Center for Staphylococcal Research (CSR) has generated a sequence …
High-resolution phenotypic profiling defines genes essential for mycobacterial growth and cholesterol catabolism
JE Griffin, JD Gawronski, MA DeJesus… - PLoS …, 2011 - journals.plos.org
The pathways that comprise cellular metabolism are highly interconnected, and alterations
in individual enzymes can have far-reaching effects. As a result, global profiling methods …
in individual enzymes can have far-reaching effects. As a result, global profiling methods …
Genes required for mycobacterial growth defined by high density mutagenesis
CM Sassetti, DH Boyd, EJ Rubin - Molecular microbiology, 2003 - Wiley Online Library
Despite over a century of research, tuberculosis remains a leading cause of infectious death
worldwide. Faced with increasing rates of drug resistance, the identification of genes that are …
worldwide. Faced with increasing rates of drug resistance, the identification of genes that are …
Tn-seq: high-throughput parallel sequencing for fitness and genetic interaction studies in microorganisms
T Van Opijnen, KL Bodi, A Camilli - Nature methods, 2009 - nature.com
Biological pathways are structured in complex networks of interacting genes. Solving the
architecture of such networks may provide valuable information, such as how …
architecture of such networks may provide valuable information, such as how …
[HTML][HTML] Molecular reconstruction of Sleeping Beauty, a Tc1-like transposon from fish, and its transposition in human cells
Members of the Tc1/mariner superfamily of transposons isolated from fish appear to be
transpositionally inactive due to the accumulation of mutations. Molecular phylogenetic data …
transpositionally inactive due to the accumulation of mutations. Molecular phylogenetic data …
Plant transposable elements: where genetics meets genomics
Transposable elements are the single largest component of the genetic material of most
eukaryotes. The recent availability of large quantities of genomic sequence has led to a shift …
eukaryotes. The recent availability of large quantities of genomic sequence has led to a shift …
Identifying genetic determinants needed to establish a human gut symbiont in its habitat
AL Goodman, NP McNulty, Y Zhao, D Leip, RD Mitra… - Cell host & …, 2009 - cell.com
The human gut microbiota is a metabolic organ whose cellular composition is determined by
a dynamic process of selection and competition. To identify microbial genes required for …
a dynamic process of selection and competition. To identify microbial genes required for …
Insights into mammalian TE diversity through the curation of 248 genome assemblies
We examined transposable element (TE) content of 248 placental mammal genome
assemblies, the largest de novo TE curation effort in eukaryotes to date. We found that …
assemblies, the largest de novo TE curation effort in eukaryotes to date. We found that …