Basic human functions such as breathing and digestion require mechanical stretching of
cells and tissues. However, when it comes to laboratory experiments, the mechanical …

Cells spread on surfaces and within three-dimensional (3-D) matrixes as they grow, divide,
and move. Both chemical and physical signals orchestrate spreading during normal …

Enterovirus A71 causes severe disease upon systemic infection, sometimes leading to life-
threatening neurological dysfunction. However, in most cases infection is asymptomatic and …

Cells living in geometrically confined microenvironments are ubiquitous in various
physiological processes, eg, wound closure. However, it remains unclear whether and how …

For the maintenance of epithelial homeostasis, various aberrant or dysfunctional cells are
actively eliminated from epithelial layers. This cell extrusion process mainly falls into two …

Programmed cell death, notably apoptosis, is an essential guardian of tissue homeostasis
and an active contributor of organ shaping. While the regulation of apoptosis has been …

Ceragenins (CSAs) are synthetic, lipid-based molecules that display activities of natural
antimicrobial peptides. Previous studies demonstrated their high in vitro activity against …

Cell competition is a process by which cells with different properties compete with each
other for survival and space, and consequently suboptimal/abnormal cells are often …

Subversion of the host cell cytoskeleton is a virulence attribute common to many bacterial
pathogens. On mucosal surfaces, bacteria have evolved distinct ways of interacting with the …

Pathogenic bacteria evolve multiple strategies to hijack host cells for intracellular survival
and persistent infections. Previous studies have revealed the intricate interactions between …