[HTML][HTML] Mesenchymal stromal cells: putative microenvironmental modulators become cell therapy

M Krampera, K Le Blanc - Cell stem cell, 2021 - cell.com
An exceptional safety profile has been shown in a large number of cell therapy clinical trials
that use mesenchymal stromal cells (MSCs). However, reliable potency assays are still …

Heart transplantation: focus on donor recovery strategies, left ventricular assist devices, and novel therapies

MG Crespo-Leiro, MR Costanzo… - European heart …, 2022 - academic.oup.com
Heart transplantation is advocated in selected patients with advanced heart failure in the
absence of contraindications. Principal challenges in heart transplantation centre around an …

[HTML][HTML] Clinical outcomes from the Assessing Donor-derived cell-free DNA Monitoring Insights of kidney Allografts with Longitudinal surveillance (ADMIRAL) study

L Bu, G Gupta, A Pai, S Anand, E Stites, I Moinuddin… - Kidney international, 2022 - Elsevier
The use of routine monitoring of donor-derived cell-free DNA (dd-cfDNA) after kidney
transplant may allow clinicians to identify subclinical allograft injury and intervene prior to …

[图书][B] Clinical anesthesia

PG Barash - 2009 - books.google.com
The premier single-volume reference in the field of anesthesia, Clinical Anesthesia is now in
its Sixth Edition, with thoroughly updated coverage, a new full-color design, and a revamped …

The trifecta study: comparing plasma levels of donor-derived cell-free DNA with the molecular phenotype of kidney transplant biopsies

PF Halloran, J Reeve, KS Madill-Thomsen… - Journal of the …, 2022 - journals.lww.com
Background The relationship between the donor-derived cell-free DNA fraction (dd-cfDNA
[%]) in plasma in kidney transplant recipients at time of indication biopsy and gene …

Donor-derived cell-free DNA as a diagnostic tool in transplantation

M Oellerich, K Budde, B Osmanodja… - Frontiers in …, 2022 - frontiersin.org
There is a need to improve personalized immunosuppression in organ transplantation to
reduce premature graft loss. Biomarkers are needed to better detect rejection, asymptomatic …

Cardiovascular magnetic resonance for rejection surveillance after cardiac transplantation

C Anthony, M Imran, J Pouliopoulos, S Emmanuel… - Circulation, 2022 - Am Heart Assoc
Background: Endomyocardial biopsy (EMB) is the gold standard method for surveillance of
acute cardiac allograft rejection (ACAR) despite its invasive nature. Cardiovascular …

Cell-free DNA reveals distinct pathology of multisystem inflammatory syndrome in children

TE Andargie, K Roznik, N Redekar, T Hill, W Zhou… - The Journal of clinical …, 2024 - jci.org
Multisystem inflammatory syndrome in children (MIS-C) is a rare but life-threatening
hyperinflammatory condition induced by infection with severe acute respiratory syndrome …

The molecular microscope diagnostic system: assessment of rejection and injury in heart transplant biopsies

PF Halloran, KS Madill-Thomsen - Transplantation, 2023 - journals.lww.com
This review describes the development of the Molecular Microscope Diagnostic System
(MMDx) for heart transplant endomyocardial biopsies (EMBs). MMDx-Heart uses …

[HTML][HTML] Donor-derived cell-free DNA levels predict graft injury in liver transplant recipients

J Levitsky, M Kandpal, K Guo, S Kleiboeker… - American Journal of …, 2022 - Elsevier
Donor-derived cell-free DNA (dd-cfDNA) has been evaluated as a rejection marker in organ
transplantation. This study sought to assess the utility of dd-cfDNA to diagnose graft injury in …