The origin of Metazoa: a unicellular perspective

A Sebé-Pedrós, BM Degnan, I Ruiz-Trillo - Nature Reviews Genetics, 2017 - nature.com
The first animals evolved from an unknown single-celled ancestor in the Precambrian
period. Recently, the identification and characterization of the genomic and cellular traits of …

The origin of animals: an ancestral reconstruction of the unicellular-to-multicellular transition

N Ros-Rocher, A Pérez-Posada, MM Leger… - Open …, 2021 - royalsocietypublishing.org
How animals evolved from a single-celled ancestor, transitioning from a unicellular lifestyle
to a coordinated multicellular entity, remains a fascinating question. Key events in this …

The origin of metazoan multicellularity: a potential microbial black swan event

I Ruiz-Trillo, K Kin, E Casacuberta - Annual Review of …, 2023 - annualreviews.org
The emergence of animals from their unicellular ancestors is a major evolutionary event.
Thanks to the study of diverse close unicellular relatives of animals, we now have a better …

Evolution and functional cross‐talk of protein post‐translational modifications

P Beltrao, P Bork, NJ Krogan… - Molecular systems …, 2013 - embopress.org
Protein post‐translational modifications (PTM s) allow the cell to regulate protein activity and
play a crucial role in the response to changes in external conditions or internal states …

The Capsaspora genome reveals a complex unicellular prehistory of animals

H Suga, Z Chen, A De Mendoza, A Sebé-Pedrós… - Nature …, 2013 - nature.com
To reconstruct the evolutionary origin of multicellular animals from their unicellular
ancestors, the genome sequences of diverse unicellular relatives are essential. However …

Genome of Acanthamoeba castellanii highlights extensive lateral gene transfer and early evolution of tyrosine kinase signaling

M Clarke, AJ Lohan, B Liu, I Lagkouvardos, S Roy… - Genome biology, 2013 - Springer
Abstract Background The Amoebozoa constitute one of the primary divisions of eukaryotes,
encompassing taxa of both biomedical and evolutionary importance, yet its genomic …

Premetazoan genome evolution and the regulation of cell differentiation in the choanoflagellate Salpingoeca rosetta

SR Fairclough, Z Chen, E Kramer, Q Zeng, S Young… - Genome biology, 2013 - Springer
Background Metazoan multicellularity is rooted in mechanisms of cell adhesion, signaling,
and differentiation that first evolved in the progenitors of metazoans. To reconstruct the …

The origins of multicellular organisms

KJ Niklas, SA Newman - Evolution & development, 2013 - Wiley Online Library
Multicellularity has evolved in several eukaryotic lineages leading to plants, fungi, and
animals. Theoretically, in each case, this involved (1) cell‐to‐cell adhesion with an …

Dynamics of genomic innovation in the unicellular ancestry of animals

X Grau-Bove, G Torruella, S Donachie, H Suga… - Elife, 2017 - elifesciences.org
Which genomic innovations underpinned the origin of multicellular animals is still an open
debate. Here, we investigate this question by reconstructing the genome architecture and …

[PDF][PDF] Acanthamoeba

NA Khan - Biology and pathogenesis, 2009 - caister.com
1. A host for viruses 2. A host for yeast 3. A host for protists 4. Acanthamoeba and bacteria
interactions 5. Is Acanthamoebaan evolutionary ancestor of macrophages? 6 …