Tumor abnormality-oriented nanomedicine design

Q Zhou, J Xiang, N Qiu, Y Wang, Y Piao, S Shao… - Chemical …, 2023 - ACS Publications
Anticancer nanomedicines have been proven effective in mitigating the side effects of
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …

Understanding nanoparticle endocytosis to improve targeting strategies in nanomedicine

MS de Almeida, E Susnik, B Drasler… - Chemical society …, 2021 - pubs.rsc.org
Nanoparticles (NPs) have attracted considerable attention in various fields, such as
cosmetics, the food industry, material design, and nanomedicine. In particular, the fast …

Cellular uptake of nanoparticles: journey inside the cell

S Behzadi, V Serpooshan, W Tao, MA Hamaly… - Chemical society …, 2017 - pubs.rsc.org
Nanoscale materials are increasingly found in consumer goods, electronics, and
pharmaceuticals. While these particles interact with the body in myriad ways, their beneficial …

Dynamic light scattering and transmission electron microscopy in drug delivery: a roadmap for correct characterization of nanoparticles and interpretation of results

SK Filippov, R Khusnutdinov, A Murmiliuk, W Inam… - Materials …, 2023 - pubs.rsc.org
In this focus article, we provide a scrutinizing analysis of transmission electron microscopy
(TEM) and dynamic light scattering (DLS) as the two common methods to study the sizes of …

Dual roles of graphene oxide to attenuate inflammation and elicit timely polarization of macrophage phenotypes for cardiac repair

J Han, YS Kim, MY Lim, HY Kim, S Kong, M Kang… - Acs Nano, 2018 - ACS Publications
Development of localized inflammatory environments by M1 macrophages in the cardiac
infarction region exacerbates heart failure after myocardial infarction (MI). Therefore, the …

Nanoparticle entry into cells; the cell biology weak link

G Griffiths, J Gruenberg, M Marsh, J Wohlmann… - Advanced Drug Delivery …, 2022 - Elsevier
Nanoparticles (NP) are attractive options for the therapeutic delivery of active
pharmaceutical drugs, proteins and nucleic acids into cells, tissues and organs. Research …

Platinum nanozymes recover cellular ROS homeostasis in an oxidative stress-mediated disease model

M Moglianetti, E De Luca, D Pedone, R Marotta… - Nanoscale, 2016 - pubs.rsc.org
In recent years, the use of nanomaterials as biomimetic enzymes has attracted great interest.
In this work, we show the potential of biocompatible platinum nanoparticles (Pt NPs) as …

Bacteriophage uptake by mammalian cell layers represents a potential sink that may impact phage therapy

MC Bichet, WH Chin, W Richards, YW Lin… - Iscience, 2021 - cell.com
It is increasingly apparent that bacteriophages, viruses that infect bacteria and more
commonly referred to as simply phages, have tropisms outside their bacterial hosts. Using …

Size‐Dependent Cytotoxicity and Genotoxicity of Silver Nanoparticles in Cochlear Cells In Vitro

M Perde-Schrepler, A Florea, I Brie… - Journal of …, 2019 - Wiley Online Library
Silver nanoparticles (AgNPs) have been proven to have potent antibacterial properties,
offering an attractive alternative to antibiotics in the treatment of several infections such as …

Mesoporous silica materials as drug delivery:“The Nightmare” of bacterial infection

M Martínez-Carmona, YK Gun'ko, M Vallet-Regí - Pharmaceutics, 2018 - mdpi.com
Mesoporous silica materials (MSM) have a great surface area and a high pore volume,
meaning that they consequently have a large loading capacity, and have been …