Drugs are typically small molecules that are generally classified as xenobiotics, which are
foreign to the human body. Several endogenous molecules, however, such as steroids and …

Metabolite identification (Met ID) is important during the early stages of drug discovery and
development, as the metabolic products may be pharmacologically active or toxic in nature …

Background: Salidroside is a glucoside of tyrosol found mostly in the roots of Rhodiola spp. It
exhibits diverse biological and pharmacological properties. In the last decade, enormous …

Antibiotics were initially natural substances. However, nowadays, they also include synthetic
drugs, which show their activity against bacteria, killing or inhibiting their growth and …

We determined 12 polybrominated diphenyl ethers (PBDEs) and 19 polychlorinated
biphenyls (PCBs) congeners in eight different brands of commercial whole milk (WM) and fat …

A plethora of active compounds found in herbal medicines can serve as substrate for
enzymes involved in the metabolism of xenobiotics. When a medicinal plant is co …

Adverse drug reactions (ADRs) are an important cause of morbidity and mortality. Genetic
factors predispose to many ADRs, affecting susceptibility to both type A and type B reactions …

The health benefits of green tea and its main constituent (-)-epigallocatechin gallate [(-)-
EGCG] have been widely supported by results from epidemiological, cell culture, animal and …

More than 80% of the global population depends on traditional medicine for their basic
primary health care needs. Africa has a well-established history of botanicals use. These …

This study evaluates the impact of physiologically relevant oxygen tensions on the response
of HepG2 cells to known inducers and hepatotoxic drugs. We compared transcriptional …