Porcine circovirus type 2 (PCV2) vaccines in the context of current molecular epidemiology

AK Karuppannan, T Opriessnig - Viruses, 2017 - mdpi.com
Porcine circovirus type 2 (PCV2) is an economically important swine pathogen and,
although small, it has the highest evolution rate among DNA viruses. Since the discovery of …

Porcine circovirus 2 genotypes, immunity and vaccines: Multiple genotypes but one single serotype

G Franzo, J Segalés - Pathogens, 2020 - mdpi.com
Identified for the first time in the 1990s, Porcine circovirus 2 (PCV-2) should not be
considered an emerging virus anymore. Nevertheless, many aspects of its biology and …

Porcine circovirus 2 (PCV-2) genotype update and proposal of a new genotyping methodology

G Franzo, J Segalés - PloS one, 2018 - journals.plos.org
Porcine circovirus 2 (PCV-2) is one of the most widespread viral infections of swine, causing
a remarkable economic impact because of direct losses and indirect costs for its control. As …

The natural history of porcine circovirus type 2: from an inoffensive virus to a devastating swine disease?

J Segalés, T Kekarainen, M Cortey - Veterinary microbiology, 2013 - Elsevier
The present review summarizes the current knowledge on the natural history of porcine
circovirus type 2 (PCV2) infection and its related diseases. The perception about PCV2 as a …

Porcine circovirus type 2 (PCV2) vaccination of conventional pigs prevents viremia against PCV2 isolates of different genotypes and geographic origins

M Fort, M Sibila, A Allepuz, E Mateu, F Roerink… - Vaccine, 2008 - Elsevier
The efficacy of recently developed porcine circovirus type 2 (PCV2) vaccines has not been
tested yet against PCV2 isolates of the two proposed genotypes. In the present work, the …

Recent advances in the epidemiology, diagnosis and control of diseases caused by porcine circovirus type 2

L Grau-Roma, L Fraile, J Segalés - The Veterinary Journal, 2011 - Elsevier
Post-weaning multisystemic wasting syndrome (PMWS) emerged as a significant disease
affecting pig production in the 1990s although the causal agent, porcine circovirus type 2 …

A proposal on porcine circovirus type 2 (PCV2) genotype definition and their relation with postweaning multisystemic wasting syndrome (PMWS) occurrence

L Grau-Roma, E Crisci, M Sibila, S Lopez-Soria… - Veterinary …, 2008 - Elsevier
Porcine circovirus type 2 (PCV2) is the essential infectious agent of postweaning
multisystemic wasting syndrome (PMWS). Despite first sequencing studies did not find any …

[HTML][HTML] The emergence of porcine circovirus 2b genotype (PCV-2b) in swine in Canada

CA Gagnon, D Tremblay, P Tijssen… - The Canadian …, 2007 - ncbi.nlm.nih.gov
Since late 2004, the swine industry in the province of Quebec has experienced a significant
increase in death rate related to postweaning multisystemic wasting syndrome (PMWS). To …

Porcine circovirus: a historical perspective

J Ellis - Veterinary pathology, 2014 - journals.sagepub.com
Porcine circoviruses (PCVs) belong to the genus Circovirus and the family Circoviridae, and
they are the smallest known viruses that replicate autonomously in mammalian cells. They …

Differences in virulence among porcine circovirus type 2 isolates are unrelated to cluster type 2a or 2b and prior infection provides heterologous protection

T Opriessnig, S Ramamoorthy… - Journal of general …, 2008 - microbiologyresearch.org
Porcine circovirus type 2 (PCV2) is divided into two genetic clusters designated PCV2a and
PCV2b. The objectives of this study were to determine whether isolates from different …