[HTML][HTML] Prospective of 68Ga-radiopharmaceutical development

I Velikyan - Theranostics, 2014 - ncbi.nlm.nih.gov
Abstract Positron Emission Tomography (PET) experienced accelerated development and
has become an established method for medical research and clinical routine diagnostics on …

Biomarkers and molecular probes for cell death imaging and targeted therapeutics

BA Smith, BD Smith - Bioconjugate chemistry, 2012 - ACS Publications
Cell death is a critically important biological process. Disruption of homeostasis, either by
excessive or deficient cell death, is a hallmark of many pathological conditions. Recent …

Glutathione-responsive biodegradable polyurethane nanoparticles for lung cancer treatment

R Iyer, T Nguyen, D Padanilam, C Xu, D Saha… - Journal of Controlled …, 2020 - Elsevier
Lung cancer is one of the major causes of cancer-related deaths worldwide. Stimuli-
responsive polymers and nanoparticles, which respond to exogenous or endogenous …

In vivo optical imaging of acute cell death using a near-infrared fluorescent zinc− dipicolylamine probe

BA Smith, ST Gammon, S Xiao, W Wang… - Molecular …, 2011 - ACS Publications
Cell death is a fundamental biological process that is present in numerous disease
pathologies. Fluorescent probes that detect cell death have been developed for a myriad of …

Positron emitting [68Ga] Ga-based imaging agents: chemistry and diversity

I Velikyan - Medicinal Chemistry, 2011 - ingentaconnect.com
Positron Emission Tomography (PET) field and, in particular utilization of 68Ga radiometal is
getting momentum. The development of new imaging agents for targeted, pre-targeted, non …

Solvent effects on the luminescent properties based on bis (hydroxy-naphthoic acid): syntheses, crystal structure and Hirshfeld analysis

YR Xi, CC Xu, SJ Yang, SC Wang, WC Sun… - Journal of Molecular …, 2023 - Elsevier
A set of novel compounds based on bis (hydroxyl-naphthoic acid), namely, B26· G [G= N, N-
dimethyl formamide (1), N, N-dimethyl acetamide (2), and N-methyl pyrrolidone (3)(B26= 5 …

Avenues to molecular imaging of dying cells: Focus on cancer

AA Rybczynska, HH Boersma… - Medicinal research …, 2018 - Wiley Online Library
Successful treatment of cancer patients requires balancing of the dose, timing, and type of
therapeutic regimen. Detection of increased cell death may serve as a predictor of the …

Catechol-based functionalizable ligands for gallium-68 positron emission tomography imaging

MA Joaqui-Joaqui, MK Pandey, A Bansal… - Inorganic …, 2020 - ACS Publications
Four tris-bidentate catecholamide (CAM) ligands were synthesized, characterized, and
evaluated as ligands for radiolabeling of gallium-68 for positron emission tomography (PET) …

In Vivo Evaluation of Gallium‐68‐Labeled IRDye800CW as a Necrosis Avid Contrast Agent in Solid Tumors

MCM Stroet, E de Blois, J Haeck… - Contrast Media & …, 2021 - Wiley Online Library
Necrosis only occurs in pathological situations and is directly related to disease severity
and, therefore, is an important biomarker. Tumor necrosis occurs in most solid tumors due to …

In Vivo Molecular Imaging of Apoptosisand Necrosis in Atherosclerotic PlaquesUsing MicroSPECT-CT and MicroPET-CT Imaging

M De Saint-Hubert, M Bauwens, N Deckers… - Molecular imaging and …, 2014 - Springer
Purpose The purpose of this paper is to study molecular imaging of apoptosis and necrosis,
two key players in atherosclerosis instability, using a multimodal imaging approach …