Synthesis of the new analogs of morpholine and their antiplasmodial evaluation against the human malaria parasite Plasmodium falciparum

C Upadhyay, N Sharma, S Kumar, PP Sharma… - New Journal of …, 2022 - pubs.rsc.org
A series of morpholine analogs functionalized with hydroxyethylamine (HEA)
pharmacophore was synthesized and assayed for the initial screening against Plasmodium …

The Multistage Antimalarial Compound Calxinin Perturbates P. falciparum Ca2+ Homeostasis by Targeting a Unique Ion Channel

Y Gupta, N Sharma, S Singh, JG Romero, V Rajendran… - Pharmaceutics, 2022 - mdpi.com
Malaria elimination urgently needs novel antimalarial therapies that transcend resistance,
toxicity, and high costs. Our multicentric international collaborative team focuses on …

In silico validation of novel inhibitors of malarial aspartyl protease, plasmepsin V and antimalarial efficacy prediction

PP Sharma, S Kumar, K Kaushik, A Singh… - Journal of …, 2022 - Taylor & Francis
Abstract Plasmepsin V (Plm V) is an essential aspartic protease required for survival of the
malaria parasite, Plasmodium falciparum (Pf). Plm V is required for cleaving the PEXEL …

Synthesis, Antiproliferative and Antimalarial Activities of Dinuclear Silver (I) Complexes with Triphenylphosphine and Thiosemicarbazones Ligands

NAFM Khir, MRMA Razak, FJ Nordin… - Indonesian Journal of …, 2021 - journal.ugm.ac.id
A series of six sulfur-bridged dinuclear silver (I) thiosemicarbazone complexes were
synthesized through the reaction of silver (I) nitrate with 4-phenyl-3-thiosemicarbazone …

A review on onychine and its analogs: synthesis and biological activity

CRB Gomes, MVN de Souza… - Current Organic …, 2020 - ingentaconnect.com
Background: Onychine is a 4-azafluorenone alkaloid isolated from the Annonaceae family,
in low concentrations. Onychine and its analogs exhibit a wide range of pharmacological …

Methodology to streamline flow cytometric-based detection of early stage Plasmodium parasitemia in mice

M Liu, MJ Liao, CJ Fisher, RDV Miguel… - Journal of microbiological …, 2022 - Elsevier
Murine infection models are needed to develop therapeutics and vaccines to combat the
Plasmodium parasites causing malaria. Herein, we describe an easy to perform flow …

[PDF][PDF] Poonam; et al. The Multistage Antimalarial Compound Calxinin Perturbates P. Falciparum Ca2+ Homeostasis by Targeting a Unique Ion Channel …

Y Gupta, N Sharma, S Singh, JG Romero, V Rajendran… - 2022 - researchgate.net
Malaria elimination urgently needs novel antimalarial therapies that transcend resistance,
toxicity, and high costs. Our multicentric international collaborative team focuses on …

[PDF][PDF] Synthesis, Antiproliferative and Antimalarial Activities of Dinuclear Silver (I) Complexes with Triphenylphosphine and Thiosemicarbazones Ligands Nur Adila …

FM Sofyan, NF Rajab, R Sarip - pdfs.semanticscholar.org
A series of six sulfur-bridged dinuclear silver (I) thiosemicarbazone complexes were
synthesized through the reaction of silver (I) nitrate with 4-phenyl-3-thiosemicarbazone …

Synthesis, Structural Characterization and Biological Activities of Ag (I) Complexes with Mixed Ligands of Thiosemicarbazone and Triphenylphosphine.

NAFM Khir - 2019 - search.proquest.com
Six Ag (I) complexes containing mixed ligand of thiosemicarbazone derivatives and
triphenylphosphine were synthesized. The structural information of the ligands and its silver …