The growth hormone receptor: mechanism of receptor activation, cell signaling, and physiological aspects

F Dehkhoda, CMM Lee, J Medina… - Frontiers in …, 2018 - frontiersin.org
The growth hormone receptor (GHR), although most well known for regulating growth, has
many other important biological functions including regulating metabolism and controlling …

Long‐term safety of growth hormone—A combined registry analysis

K Stochholm, W Kiess - Clinical endocrinology, 2018 - Wiley Online Library
Objectives Preliminary data from the French cohort of the Safety and Appropriateness of
Growth hormone treatments in Europe (SAG hE) study raised concerns regarding the safety …

Long-term safety of recombinant human growth hormone in children

J Bell, KL Parker, RD Swinford… - The Journal of …, 2010 - academic.oup.com
Abstract Background: Between 1985 and 2006, the National Cooperative Growth Study
(NCGS) monitored the safety and efficacy of recombinant human growth hormone (rhGH) in …

Effect of serotesting with counselling on condom use and seroconversion among HIV discordant couples in Africa.

S Allen, J Tice, P Van de Perre, A Serufilira… - British medical …, 1992 - bmj.com
OBJECTIVE--To determine whether HIV testing and counselling increased condom use and
decreased heterosexual transmission of HIV in discordant couples. DESIGN--Prospective …

Risk of disease recurrence and second neoplasms in survivors of childhood cancer treated with growth hormone: a report from the Childhood Cancer Survivor Study

CA Sklar, AC Mertens, P Mitby… - The Journal of …, 2002 - academic.oup.com
GH deficiency is common in survivors of childhood cancer, especially in those treated with
radiation to the brain. The impact of GH therapy on disease recurrence has been studied in …

Increased incidence of neoplasia in patients with pituitary adenomas

V Popovic, S Damjanovic, D Micic… - Clinical …, 1998 - Wiley Online Library
OBJECTIVE The goal of our study was to determine the rate of neoplasms in patients with
other pituitary adenomas (non‐functioning and prolactinomas) in comparison with …

Safety outcomes during pediatric GH therapy: final results from the prospective GeNeSIS observational program

CJ Child, AG Zimmermann, GP Chrousos… - The Journal of …, 2019 - academic.oup.com
Context Safety concerns have been raised regarding premature mortality, diabetes,
neoplasia, and cerebrovascular disease in association with GH therapy. Objective To …

Outbreaks of enterohaemorrhagic Escherichia colt O157: H7 infection by two different genotype strains in Japan, 1996

H Watanabe, A Wada, Y Inagaki, K Itoh, K Tamura - The Lancet, 1996 - thelancet.com
The patient was born at 42 weeks of gestation with intrauterine growth retardation of
unknown cause. His birth weight was 2300 g and body length 44 cm. At the age of 5 years 7 …

IGFs and IGFBPs: role in health and disease

R Monzavi, P Cohen - Best Practice & Research Clinical Endocrinology & …, 2002 - Elsevier
The insulin-like growth factors (IGFs), IGF-binding proteins (IGFBPs), and IGFBP proteases
are the main regulators of somatic growth and cellular proliferation. IGFs are involved in …

Growth hormone deficiency and treatment in childhood cancer survivors

NI Pollock, LE Cohen - Frontiers in Endocrinology, 2021 - frontiersin.org
Growth hormone (GH) deficiency is a common pituitary hormone deficiency in childhood
cancer survivors (CCS). The identification, diagnosis, and treatment of those individuals at …