Drug delivery systems (DDSs) play an important role in delivering active pharmaceutical
ingredients (APIs) to targeted sites with a predesigned release pattern. The chemical and …

The properties of pharmaceutical powders, and the liquid binder, directly influence the
penetration behavior in the wet granulation process of the pharmaceutical industry …

A challenge in agitated drying is to take information from the laboratory scale and use it to
scale up the process to the manufacturing scale. In this study, we focus on scale-up of the …

Monitoring the microstructure of the granule in the wet granulation process could play a
decisive role in obtaining high‐quality granules. Due to the complex, fast and opaque nature …

Drying time, velocity, and temperature are important aspects of the drying process for
pharmaceutical granules observed during tablet manufacturing. However, the drying …

Single-drop granulation is performed under a variety of conditions to characterize the
behavior that results from a liquid droplet impacting a powder bed. Drop impact velocity …

Understanding the mixing behavior that unfolds when liquid droplets impact on powder beds
requires a sub-surface dynamic imaging method that provides high spatial and temporal …

Synchrotron radiation based dynamic micro-computed tomography (micro-CT) is a powerful
technique available at synchrotron light sources for investigating evolving microstructures …

Chemical fertilizers, such as potash, have a strong tendency to cake when exposed to
humidity. In this work, a novel synchrotron-based X-ray tomography 3D-imaging technique …

Powder mixing unit operations are essential to the manufacturing of pharmaceutical drug
substance and drug products. To model powder mixing, computational approaches have …