Approximately 5% of the world-wide population is affected by autoimmune diseases.
Overall, autoimmune diseases are still difficult to treat, impose a high burden on patients …

Chronic inflammation is the main feature of many long-term inflammatory diseases such as
autoimmune diseases, metabolic disorders, and cancer. There is a growing number of …

Background The new types of mRNA-containing lipid nanoparticle vaccines BNT162b2 and
mRNA-1273 and the adenovirus-based vaccine AZD1222 were developed against SARS …

Respiratory syncytial virus (RSV) infection is a major cause of severe lower respiratory tract
infection and death in young infants and the elderly. With no effective prophylactic treatment …

Antibodies play a critical role in linking the adaptive immune response to the innate immune
system. In humans, antibodies are categorized into five classes, IgG, IgM, IgA, IgE, and IgD …

Each severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant renews
concerns about decreased vaccine neutralization weakening efficacy. However, while …

Antibodies play a critical role in protection against influenza; yet titers and viral neutralization
represent incomplete correlates of immunity. Instead, the ability of antibodies to leverage the …

The microbially-derived short-chain fatty acid butyrate is a central inhibitor of inflammatory
innate and adaptive immune responses. Emerging evidence suggests that butyrate induces …

Immunoglobulin glycosylation is a pivotal mechanism that drives the diversification of
antibody functions. The composition of the IgG glycome is influenced by environmental …

The pathobiont Staphylococcus aureus (Sa) induces nonprotective antibody imprints that
underlie ineffective staphylococcal vaccination. However, the mechanism by which Sa …